Royal Surrey County Hospital

Laparoscopic versus open emergency colonic resection for obstruction: a multicentre retrospective cohort study

Abstract Background Despite its established benefits in elective colorectal surgery, the adoption of laparoscopy in the emergency setting remains limited. This retrospective international multicentre study assesses laparoscopic and open colonic resection in patients with acute be...

Acute kidney injury and renal replacement therapy: a critical synthesis of metabolic derangements and nutritional implications

Acute kidney injury (AKI) affects up to 50% of critically ill patients and is frequently complicated by severe metabolic derangements, requiring the initiation of replacement therapy (RRT) in 10–15% of cases. Despite substantial progress in the diagnosis of AKI and optimisation o...

The Use of Extracorporeal Organ Support Therapies for Acute Kidney Injury in Cancer Patients

Acute kidney injury (AKI) is a frequent and serious complication in patients with cancer, associated not only with increased morbidity and mortality, but also with the interruption or modification of anticancer therapy. In critically ill patients with cancer, AKI arises from a co...