Institution
Royal London Hospital
Recent research
- Health & MedicineOpen access
Predictive Models of Morbidity and Mortality in Gynaecological Cancer Surgery: A Systematic Review
Background/Objectives: Gynaecological–oncological surgery involves substantial perioperative morbidity and mortality risks. Reliable preoperative risk stratification could inform consent, shared decision-making and perioperative optimisation. Several prediction models exist, but...
- Health & MedicineOpen access
Abstract Objectives To evaluate the early comparative effectiveness of robotic versus conventional total hip replacement (THR) in the UK. Design Target trial emulation study. Setting Public and private hospitals using data from the National Joint Registry of England, Wales, North...
- Health & MedicineOpen access
Association Between Genetic Ancestry and Multiple Sclerosis Severity
OBJECTIVE: The objective of this study was to determine whether genetic ancestry is associated with differences in the clinical course of multiple sclerosis (MS). METHODS: Participants with MS living in the United Kingdom >18 years old were recruited from 2021 to 2025 and genotyp...
- BiologyOpen access
The standard clinical genetic testing model for hereditary cancers applies stringent eligibility criteria and consistently misses large numbers of at-risk cancer-susceptibility-gene (CSG) carriers in the general population, leading to missed opportunities for cancer screening/pre...
- Health & MedicineOpen access
Abstract Hematopoietic cell transplantation, cellular and gene therapies, and (CAR)-T cells have revolutionized outcomes in hematologic disorders. However, major disparities persist in their availability, accessibility, and affordability, particularly in low- and middle-income co...