Royal Hospital for Women

Sodium butyrate rescues long-term neurodevelopmental deficits following perinatal methadone exposure

Abstract Background Prenatal opioid exposure (POE) induces long-term neurodevelopmental, behavioral and cognitive deficits for which no targeted treatments are available. The mechanisms underlying POE deficits are poorly understood, but have been linked to a range of central, per...

Oxygen vs Air at Birth for Moderate- to Late-Preterm Infants

Importance The optimal initial fraction of inspired oxygen (F io 2 ) for delivery room resuscitation of neonates born at 32 to 35 weeks’ gestation is unknown. Objective To compare outcomes for neonates born at 32 to 35 weeks’ gestation when initiating resuscitation with F io 2 0....

Parent and child preferences for a community-based physical activity participation intervention for children born very preterm: a qualitative framework analysis

PURPOSE: Children born very preterm (VP: <32 weeks' gestation) are less physically active than their term-born peers and face greater barriers to participation in community-based activities. This study consults with key knowledge holders (children born VP and their parents) to un...