Royal Hospital for Children

Managing growth and puberty concerns in individuals with Duchenne muscular dystrophy: Updated guidance and future directions

Long-term glucocorticoid therapy is standard of care for individuals with Duchenne muscular dystrophy (DMD) but often results in impaired growth and delayed or incomplete puberty, impacting their physical and psychosocial health. Although DMD endocrine care has evolved, leading t...

‘It’s not fair!’ Fathers’ perceptions of injustice in the context of pediatric chronic pain: An interpretative phenomenological analysis

Recent research highlights the role of parental appraisals in pediatric pain, yet studies on injustice appraisals remain limited and largely focused on mothers. This qualitative study explores fathers' appraisals of injustice in the context of their child's chronic pain, examinin...

Selective immunoglobulin A deficiency and coeliac disease: Immune response dynamics

Abstract Objective To analyse the serological immune response in paediatric patients with selective immunoglobulin A deficiency (SIgAD) and coeliac disease (CeD), focusing on immunoglobulin G antibody dynamics after starting the gluten‐free diet (GFD). Methods Data from SIgAD pat...

Thermophysiological and perceptual responses to exercise heat stress in people with cystic fibrosis on Elexacaftor/Tezacaftor/Ivacaftor

Abstract The objective of this study was to investigate thermophysiological and perceptual responses to exercise heat stress in people with cystic fibrosis (pwCF) on Elexacaftor/Tezacaftor/Ivacaftor (ETI) versus healthy controls, and to explore their lived experiences of heat str...

Prognostic Value of Interictal Epileptiform Discharges on EEG for Neurodevelopmental Outcomes in Early-Onset Epilepsy: A Systematic Review

Poster presenting a systematic review of longitudinal studies on interictal epileptiform discharges (IEDs) as prognostic markers of neurodevelopmental outcome in children with epilepsy onset at or before 5 years of age. Five databases were searched from inception to 23 October 20...

Prognostic Value of Interictal Epileptiform Discharges on EEG for Neurodevelopmental Outcomes in Early-Onset Epilepsy: A Systematic Review

Poster presenting a systematic review of longitudinal studies on interictal epileptiform discharges (IEDs) as prognostic markers of neurodevelopmental outcome in children with epilepsy onset at or before 5 years of age. Five databases were searched from inception to 23 October 20...

Protein-Containing Breakfasts Are Associated with Reduced Postprandial Glycaemic Excursions in Children and Young People with Type 1 Diabetes: A Pragmatic Study

Background/Objectives: This study examined whether adding 10 g of protein to a high glycaemic index (GI) breakfast could attenuate postprandial glycaemic responses in children and young people (CYP) with type 1 diabetes (T1D). Postprandial glucose responses following this modifie...