Roswell Park Comprehensive Cancer Center

“I never thought to bring them up to the doctor”: examining symptom appraisal, help-seeking behaviors, and diagnostic delays among young adults with cancer

Abstract Purpose Cancer incidence is rising among young adults (20–39 years), and it is one of the top five causes of death for this age group. Young adults often experience longer delays in diagnosis than children and older adults, which negatively impacts survival and quality o...

Raman spectroscopic identification of biochemical alterations in Alzheimer’s disease brain tissue

<title>Abstract</title> Alzheimer’s disease (AD) is a progressive neurodegenerative disorder marked by chronic inflammation, neuronal loss, and continuous decline in memory and cognitive function. Raman Spectroscopy (RS) offers a powerful, label‑free approach for detecting early...

Multimodal radiopathological integration for prognosis of limited and extensive stage small cell lung cancer

Small-cell lung cancer (SCLC) is an aggressive malignancy with poor survival and no validated prognostic biomarkers. We developed and validated a multimodal artificial intelligence–based radiopathomic framework to predict progression-free survival (PFS) by integrating radiologic...

Top 10 Tips Palliative Care Clinicians Should Know About Preventing Burnout

Health care worker burnout is a potential job hazard. Palliative care clinicians (PCCs) are especially vulnerable due to the intense emotional and challenging demands of the work. Creating environments for PCCs to thrive is the responsibility of the organization, however, PCCs ha...