Rose Research Center (United States)

Combination bupropion–zonisamide facilitates rapid reduction in smoke exposure and prevents weight gain during switching to electronic nicotine delivery systems: A randomized clinical trial

INTRODUCTION: A pilot study suggested that the combination of bupropion (BUP) and zonisamide (ZON) could facilitate smoking reduction during switching to an electronic nicotine delivery system (ENDS). This randomized controlled trial tested the hypothesis that BUP/ZON would produ...