Institution
Riverside Hospital of Guangxi Zhuang Autonomous Region
Recent research
- Health & MedicineOpen access
A major clinical dilemma in epilepsy treatment lies in the difficulty of balancing efficacy and safety. First-line antiepileptic drugs such as valproic acid (VPA) exhibit dose-dependent side effects. Enhancing γ-aminobutyric acid (GABA)ergic inhibition is a core therapeutic strat...
- Society & EconomicsOpen access
Sleep disturbances are highly prevalent among people living with HIV (PWH) and frequently co-occur with psychiatric comorbidities such as depression and anxiety. Although these factors independently predict health-related quality of life (HRQoL), the extent to which psychiatric s...
- BiologyOpen access
Metabolomics of immunosenescence: bridging blood biomarkers and metabolic pathways in aging
Immunosenescence—the progressive decline in immune competence with advancing age—contributes substantially to increased infection susceptibility, reduced vaccine efficacy, and heightened chronic inflammatory disease burden in older adults. Despite extensive characterization of im...
- BiologyOpen access
Abstract Drosha is a critical regulator of kidney development; its loss or mutation, identified in a subsets of Wilms tumor (WT), a pediatric kidney cancer, leads to nephric cap mesenchyme developmental defects. Here, we investigated the role of Drosha in mesangial cells and its...
- BiologyOpen access
Abstract Background Endoplasmic reticulum stress (ERS) is a critical pathological factor that drives myocardial infarction (MI) progression. This study aimed to screen and validate core ERS-related hub genes involved in acute myocardial infarction (AMI) pathogenesis by integratin...