RIKEN

Two stress-responsive kinases suppress ferroptosis by activating antioxidant programs under mild oxidative stress

Cancer cells maintain chronically elevated levels of reactive oxygen species (ROS) while relying on robust antioxidant programs to preserve redox homeostasis and viability. Although therapeutic strategies that disrupt this balance to induce lethal oxidative stress and ferroptosis...

Atomic-precision π-driven peptide hydrogel nanofibers with ordered water channels

Aromatic interactions organize molecules into ordered supramolecular architectures, while peptides form functional soft materials through hydrogen bonding and water-mediated assembly. In peptide-based systems, strong aromatic stacking is typically achieved by terminal capping, wh...