Richmond University Medical Center

Targeting the ENO1 metabolic checkpoint via microenvironment-responsive nanotherapeutics promotes postinfarction cardiac repair

Myocardial infarction (MI) triggers persistent inflammatory dysregulation, wherein macrophages undergo glycolytic reprogramming and adopt an inflammatory phenotype that impairs cardiac repair. However, the specific metabolic drivers underlying post-MI macrophage dysfunction remai...

Hypertension in Young Adults in Nigeria: A Review of Prevalence and Emerging Trends

Abstract Background Hypertension is increasingly being observed among young adults in low- and medium-income countries, including Nigeria. Although national estimates show a rising burden over the last three decades, the extent to which these trends affect younger populations rem...

Temporal trends and demographic disparities in constipation-associated mortality in the United States, 1999–2024

Constipation is common and managed as benign; however, refractory disease can progress through fecal impaction to stercoral colitis, perforation, and sepsis. The national mortality trends are unmapped. Serial cross-sectional CDC WONDER multiple-cause analysis, US adults ≥ 25 year...