Research Institute for Endocrine Sciences

Dietary acid load is associated with quality of life in overweight and obese adult in Iranian women: a cross sectional study

Epidemiologic investigations have shown that dietary acid load (DAL) is associated with some limited quality of life (QoL) markers; however, according to the documents available so far, the association of this dietary pattern with QoL among overweight and obese women is not clear...

Zinc and diabetes-related sarcopenia: molecular insights into muscle atrophy in diabetes

Previous reviews have discussed the pathophysiology of diabetic sarcopenia, but none have made any mention of the role of zinc (Zn). This review highlights the emerging role of Zn and Zn-related proteins as potentially important regulators of skeletal muscle mass and function, ad...

Association of total and source-specific dietary nitrate and nitrite with subclinical atherosclerosis in young adults

Atherosclerosis, a chronic process originating in young adulthood and progressing silently to clinical cardiovascular disease, highlights the need to identify modifiable nutritional exposures. Epidemiological evidence regarding their association with subclinical atherosclerosis i...

Artificial intelligence in radiographic quantification and severity assessment of peri‐implant marginal bone loss: A systematic review

ABSTRACT Purpose To critically assess artificial intelligence (AI)‐based radiographic models for quantitative measurement, localization/detection, segmentation/keypoints, diagnostic classification, and severity or morphology assessment of peri‐implant marginal bone loss (MBL) and...

Ultra-processed food consumption (NOVA index) and the odds of diabetic nephropathy in women: a case-control study

diabetic nephropathy (DN) is a major complication of diabetes mellitus associated with increased morbidity and mortality. Dietary factors, particularly unhealthy food consumption, may contribute to kidney dysfunction. This study aimed to investigate the association between the NO...

Altered expression of ZAP70 and lnc-FAHD2B-3 in colorectal polyps: an exploratory molecular study

Colorectal cancer (CRC) is a major global health concern that often develops from precursor lesions, particularly adenomatous colorectal polyps. However, the molecular alterations associated with early colorectal neoplasia remain incompletely understood. ZAP70, a signaling molecu...

The association between perceived social support and glycemic status transitions: a 3-year longitudinal study of Iranian adults

This three-year longitudinal study investigates the association of Perceived Social Support and its subscales with changes in blood-glucose status among Iranian adults. In a three-year cohort of 1,458 Iranian adults, perceived social support was measured with the 12-item Iranian...

Human-inherited RORγT deficiency encompasses genetic heterogeneity, T cell deficiency, and clinical homogeneity

Abstract We previously reported inherited RORγT deficiency in seven patients from three ancestries (Chilean, Palestinian, Saudi Arabian) with mycobacterial disease and chronic mucocutaneous candidiasis (CMC). We report here five additional patients from different ancestries (Afgh...

Ecological analysis of Cutaneous leishmaniasis incidence and climatic variability in Kashan and Aran - Bidgol, Iran (2014–2024)

Cutaneous leishmaniasis (CL) is a major neglected tropical disease whose transmission is strongly influenced by climatic and environmental conditions. This study investigated the temporal associations between climatic variables and CL incidence in Kashan and Aran and Bidgol count...

Resilient surgical instrument reprocessing during healthcare disasters and outbreaks: a systematic review of barriers, preparedness gaps and policy strategies

Surgical instrument reprocessing is essential for infection prevention and continuity of surgical care. However, evidence on barriers and adaptive strategies for maintaining reprocessing capacity during healthcare disruptions remains fragmented. This systematic review synthesized...

The effect of reduced carbohydrate diet on cardiometabolic risk factors and gut microbiota in children and adolescents with obesity: a randomized controlled trial

Abstract Objective To compare the effects of a reduced-carbohydrate diet (RCD) with a standard diet (STD) on cardiometabolic risk factors and gut microbiota composition in children and adolescents with obesity. Methods In this randomized controlled trial, 84 children and adolesce...

Tenting screw (tent pole) technique in vertical and horizontal alveolar ridge augmentations: a systematic review and meta-analysis

Abstract Purpose Providing an overview on tenting screws/tent-pole technique for space-maintenance in vertical and horizontal alveolar ridge augmentation. Methods The protocol was registered at PROSPERO (CRD420251178321). PRISMA-2020 guidelines were applied. Medline via PubMed, W...

Evaluation of Iraq’s national plan for hepatitis B control: identifying gaps and strategies for improvement

Hepatitis B virus (HBV) remains a significant public health challenge in Iraq, necessitating a comprehensive evaluation of the national hepatitis B control plan. This study aimed to assess the epidemiological trends of HBV in Iraq from 2015 to 2022 and evaluate the implementation...