Research Center Pharmaceutical Engineering (Austria)

Saponins induce lipid-dependent structural heterogeneity and modulate membrane organization in phospholipid bilayers

Abstract Saponins are amphiphilic natural compounds whose membrane activity is commonly attributed to sterol complexation, whereas their effects on sterol-free membranes remain poorly understood. Here, we investigated how lipid packing governs the interaction of a Saponaria offic...

Detection of load orientation effects in Lithium-ion batteries via electrochemical impedance spectroscopy

This study investigates the influence of load orientation effects on the impedance response of commercial lithium-ion prismatic cells. Electrochemical impedance spectroscopy (EIS) was performed during stepwise deformation using a cylindrical impactor oriented along the cell's X-d...

Rate-dependent mechanical–electrical–thermal abuse response of fresh and aged tabless 4695 cylindrical cells under radial indentation

Electrochemical aging can alter the mechanical abuse response of large-format cylindrical cells, but its effect under dynamic loading remains insufficiently resolved. This study compares fresh and aged tabless 4695 cells at 100 % State of Charge (SoC) under dynamic radial indenta...

Mechanochemistry: From Classical Grinding to Modern and Scalable Process Technologies

Mechanochemistry, the study of how mechanical energy drives chemical transformations, has rapidly evolved into a powerful and influential discipline at the intersection of chemistry and materials science. This article provides an integrated and critical overview of recent advance...

Spatio-Temporal Behavior of End-Wall Film Cooling of a Turbine Vane with Purge Flow Measured by Fast-Response Pressure-Sensitive Paint

Abstract The demand for high-efficiency, low-emission gas turbines has intensified with growing global energy consumption. In modern turbines, elevated inlet temperatures and uniform combustor-exit profiles expose the first-stage vane endwall to severe thermal loads. Complex vort...

Scale-Up of Mechanochemical Amidation in AgitatorBead Mills: From Laboratory to Commercial Scale

Abstract Bead mills are widely used in industry for particle size reduction across diverse applications; however, their use as reactors for mechanochemical synthesis has largely remained limited to laboratory studies, with no prior demonstration at a manufacturing-relevant scale....