Regional Health

Assessing a local vaccination initiative: Eight years of “Immuniser Lyon” in France

“Immuniser Lyon” (IL) is a French city-level initiative launched in 2015 to promote vaccination through coordinated, locally tailored actions. The objective of this study is to describe and compare temporal trends in vaccine coverage for HPV and influenza in the Rhône area versus...

Influence of socio-economic inequalities and healthcare organisation on HPV vaccination coverage in both sexes in the Campania region: A population-based study between 2006 and 2023

Human papillomavirus (HPV) and hepatitis B vaccinations are the only immunisation programmes that directly prevent cancer. Despite the expansion of universal, gender-neutral HPV programmes, a free and actively offered vaccination does not ensure achievement of coverage targets. W...

Implementation factors of group antenatal care in low-resource settings in Tanzania: A qualitative study using the Consolidated Framework for Implementation Research

Antenatal care (ANC) is essential for improving maternal and newborn health, yet many women do not complete the recommended follow-up visits and often experience suboptimal quality of care and weak provider-client interactions. Group antenatal care (G-ANC) offers an alternative s...

Environmental Sustainability-Related Knowledge, Behaviors, and Perceived Barriers Among Italian Intensive Care Unit Nurses: A Cross-Sectional Survey

Background/Objectives: Healthcare systems are increasingly recognized as contributors to climate change, and intensive care units represent particularly resource-intensive clinical environments. Nurses play a central role in shaping daily care practices that may influence the env...

Balancing data quality and participant burden: a comparative analysis of abbreviated vs extended symptom diaries in the CanTreatCOVID trial

Abstract Background Symptom diaries are widely used in acute respiratory infection trials to capture patient-reported symptom severity and recovery. Longer questionnaires may provide a more complete clinical picture but can increase participant burden and reduce adherence. Eviden...

The Risk of COVID-19 Death in Jamaica by Wave Period: A Cross-Sectional Analysis

Globally, the COVID-19 pandemic caused significant healthcare, economic and social impacts. This study described characteristics of COVID-19 mortality and determined risk of COVID-19 death by wave period in Jamaica. A cross-sectional analysis was conducted using data on confirmed...

Artificial intelligence for Amazonian health: validation is the price of entry

At the AI as Catalyst meeting in Manaus (July 28–29, 2026; https://ia-como-catalisadora-manaus.netlify.app), participants ran a simple exercise. Working in teams, they wrote about ten clinical cases and put each one to widely used general-purpose chatbots twice: first in standard...

Effects of ketone supplementation on metabolic and hormonal profiles in polycystic ovary syndrome

Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by metabolic dysfunction, hyperandrogenism, and reproductive hormone imbalance. This meta-analysis aimed to evaluate the effects of ketone supplementation on anthropometric, metabolic, and h...

Is there a limit to limitations? A proposal for structured limitations reporting in scientific manuscripts

Reporting studies limitations is essential for transparent interpretation. While reporting guidelines such as CONSORT, STROBE, PRISMA mandate disclosure of limitations, no widely adopted framework standardizes how these are reported in a structured and comparable format. In pract...

The Chronic Wound Microbiome: Dynamics and Treatment Response

Chronic ulcers require prolonged care and carry an increased risk of infection and limb loss. Sequencing studies of diabetic foot ulcers, venous leg ulcers, and pressure ulcers have revealed dynamic, patient-specific microbial communities whose composition varies with local tissu...

An update on the non operative reduction of intussusception at two Major Caribbean paediatric referral hospitals

A retrospective observational study was conducted to determine the success rate of non-operative management of intussusception at the two major paediatric surgical referral hospitals in Kingston, Jamaica, and to compare it to previously reported regional and international benchma...

Wastewater-BasedEpidemiology of Sexually TransmittedPathogens Across Scales

Abstract Wastewater-based epidemiology for sexually transmitted pathogens Chlamydia trachomatis (chlamydia), Neisseria gonorrhoeae (gonorrhea), and Treponema pallidum (syphilis) is sparse compared to viral targets despite their public health significance. We used multiplex, digit...

Real-world effectiveness of a multicomponent early intervention program for first episode psychosis in Emilia Romagna (Italy): Timeliness, specificity and fairness

Background This study provides a real-world evaluation of the multicomponent Emilia-Romagna First Episode Psychosis Program (RER-FEP) (2013–2019). It assesses how timeliness, treatment specificity, and socio-demographic factors related to fairness (including citizenship) are asso...