Regenstrief Institute

Keyphrase identification using minimal labeled data with hierarchical contexts and transfer learning

Interoperable clinical decision support system (CDSS) rules provide a pathway to interoperability, a well-recognized challenge in health information technology. Building an ontology facilitates creating interoperable CDSS rules, and identifying the keyphrases (KP) from the existi...

Moderators of the Effects of Telehealth Mindfulness-based Interventions for Chronic Pain

OBJECTIVES: Little is known about who benefits most from Mindfulness-Based Interventions (MBIs), and whether certain groups differentially benefit from different types of MBI formats (group-based versus non-group based). The present study uses data from a three-arm randomized con...

Tramadol Co‐Administration with Oxycodone or Hydrocodone Increases Opioid Burden without Improving Postoperative Pain Control

Tramadol is frequently co-prescribed with oxycodone or hydrocodone after surgery under the assumption that its dual mechanism of action provides an opioid-sparing benefit. However, evidence supporting this practice is limited and inconsistent. We conducted a secondary analysis of...

Chronic Smartphone Exposure as a Behavioral Science Problem: Toward a Life-Course Agenda for Health Research

Abstract Smartphones are now woven into everyday behavior across development, yet much of the evidence linking digital technology to health relies on broad exposure categories, sparse measurement, and age-siloed literatures. As a result, current research is poorly positioned to e...

Effectiveness of RSV Prevention Strategies in US Infants: 2024–2025

OBJECTIVE: In 2023, 2 products, a long-acting monoclonal antibody (nirsevimab) and maternal respiratory syncytial virus (RSV) vaccination, were recommended in the United States to prevent severe RSV disease among infants in their first RSV season. Low uptake during the 2023 to 20...