Red de Investigación en Sida

Gender, merit, and social capital in national accreditation: time to tenure‑track promotion in spanish management and organization studies

Abstract Women remain underrepresented in senior academic positions despite formal, ostensibly meritocratic promotion systems in many European countries, including Spain. National accreditation by the Spanish quality and accreditation agency (ANECA) is a mandatory gateway for pro...

Association of Native American, European, and African Ancestry with CYP450 Pharmacogenetics and Metabolic Phenotypes in Admixed Latin American Populations from Ecuador and Nicaragua

Background/Objectives: Interethnic variability significantly influences drug response, highlighting the importance of assessing genomic ancestry for personalized medicine. Although Latin American populations are highly admixed, they remain underrepresented in pharmacogenetic rese...

Tisa-cel and axi-cel CAR structure influences the development of resistance to CD19-CAR-T therapy

CD19-CAR-T cells are a major therapy for relapsed/refractory B-cell malignancies, yet ~50% of patients relapse after infusion. Clinical data suggest that tisa-cel treatment is associated with higher rates of CD19 mutation than axi-cel, though direct comparisons have been lacking....