Rabin Medical Center

Patterns and Predictors of Repeated Medication Nonadherence in Glaucoma: A Population-Based Study

Background/Objectives: We aimed to evaluate nonadherence to topical glaucoma therapy and identify risk factors for repeated prescription fulfillment failure in a large national population-based cohort. Methods: The electronic medical records from a large health maintenance organi...

Brain Gadolinium Biodistribution, Clearance, and Retention Following High-Dose Contrast-Agent Exposure in Mice: A Multimodal Study

We evaluated gadolinium biodistribution, clearance, and long-term brain retention following high-dose gadolinium-based contrast agent (GBCA) exposure in 90 mice. Macrocyclic and linear agents were assessed using particle-induced X-ray emission (PIXE) alongside complementary eleme...

Outcomes of Catheter-Free TVT-O Surgery: A Single-Center Case Series

Objectives: Stress urinary incontinence (SUI) significantly affects quality of life. Routine catheterization during and after mid-urethral sling surgery may increase morbidity, and its necessity remains uncertain. This study aimed to evaluate the safety and outcomes of transobtur...

Cutaneous Lymphoma International Prognostic Index and Risk Stratification in Advanced Mycosis Fungoides and Sézary Syndrome

Importance Risk stratification in advanced mycosis fungoides and Sézary syndrome (MF/SS) remains suboptimal given that current TNMB (tumor, node, metastasis, blood) staging has limited prognostic value for clinically relevant outcomes. Objective To determine whether the Cutaneous...

Carbapenemase-producing Kluyvera spp.: epidemiology of an evolving species

Abstract Background Kluyvera spp. are increasingly recognised as significant pathogens in humans. Recent reports of carbapenemase-producing (CP) Kluyvera spp. raise a concern that they may be disseminating carbapenemases to other species undetected. Research on CP-Kluyvera spp. i...

Discrepancies Between SNOT-22 Questionnaire, Objective Assessments, and Histopathologic Findings in Chronic Rhinosinusitis With Nasal Polyps

Background The Sinonasal Outcome Test-22 (SNOT-22) is widely used to evaluate symptom burden in chronic rhinosinusitis with nasal polyps (CRSwNP), yet its relationship with objective disease measures, pathological features, and specific endotypes remains unclear. Objective To ass...

Data and analysis code for: Regional analgesic techniques for postoperative pain after kidney transplantation: a systematic review and Bayesian meta-analysis

Extracted dataset and full analysis pipeline for a systematic review and Bayesian meta-analysis of regional analgesic techniques in adult kidney transplant recipients. Fourteen randomised controlled trials, 31 trial arms. Includes the risk-of-bias rationales, the R Markdown pipel...

Decisional regret following avoidance of epidural analgesia in labor

Epidural analgesia (EPA) is a commonly employed technique of providing pain relief during labor. However, a subset of women elects to avoid this option, motivated by personal, cultural, or medical reasons. While the clinical outcomes of EPA have been widely studied, the emotional...

From Rapid Progression to Long-Lasting Complete Response: A Wide Range of Ripretinib Activity for Metastatic GIST—A Real-World Cohort

Background: Ripretinib, a switch-control kinase inhibitor approved for advanced gastrointestinal stromal tumor (GIST), inhibits primary and secondary KIT and PDGFRA mutations. Real-world data from Western and Middle Eastern populations remain limited. We report outcomes from a mo...

Enhancing short-term predictions of mortality risk for liver transplant candidates through random survival forests

MELD-based scores do not fully account for systemic and metabolic risk in liver transplant candidates, with notable gaps for those with metabolic dysfunction-associated steatotic liver disease (MASLD). In this retrospective, outcome-anchored, single-center proof-of-concept study,...

The Global Immune–Nutrition–Inflammation Index (GINI) as a Candidate Prognostic Marker in Patients with Cutaneous Squamous Cell Carcinoma Treated with Cemiplimab

Background/Objectives: Cutaneous squamous cell carcinoma (cSCC) is a highly prevalent malignancy. While Cemiplimab has transformed the treatment landscape across various disease stages, reliable pretreatment biomarkers for risk stratification remain lacking.. The Global Immune–Nu...

Psilocybin prevents chemotherapy-induced peripheral neuropathy through mitochondrial trafficking preservation

Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling, often irreversible toxicity that affects millions of patients, limits life-saving cancer therapy, and lacks proven treatment. In this work, we show that as little as two doses of psilocybin before chemotherapy dura...

IgG4-related endobronchial lung disease and HIV: a case report and review of the literature

Immunoglobulin G4-related disease (IgG4-RD) is a systemic inflammatory disorder which typically presents as multiorgan infiltration by polyclonal IgG4-positive plasma cells and responds well to immunosuppression such as systemic corticosteroids. The co-occurrence of IgG4-RD among...

Modular Metamaterials for Adaptable MRI Signal Control: Combining Dipole Array With a New Hexagon‐Based Artificial Dielectrics

ABSTRACT Emerging concepts of metamaterials for MRI offer improved image quality through enhanced RF field control. However, current designs are often limited by bulky configurations, dielectric losses, and limited adaptability. Patient‐specific optimization—essential for improvi...

CT-based radiological score (AMESI CT-score) for severity of bowel injury in acute mesenteric ischemia

PURPOSE: To evaluate whether common bowel-related CT signs alone can reliably identify irreversible bowel injury in acute mesenteric ischemia (AMI) and to develop a radiological score to enhance reporting and assist clinical decision-making. METHODS: This ancillary analysis of th...

Pediatric Mycosis Fungoides and Hydroa Vacciniforme Lymphoproliferative Disorder

Patients most often present with hypopigmented patches, though folliculotropic disease is also common. Prognosis is usually excellent. Most patients are diagnosed with early-stage disease, and less than 5% of cases progress to late-stage disease. Pediatric MF can be difficult to...

Elacestrant in Combination with Everolimus for Estrogen Receptor-Positive, HER2-Negative Previously Treated Advanced Breast Cancer: Results from ELEVATE

PURPOSE: Treatment options for progression on first-line endocrine therapy (ET)+CDK4/6i for ER-positive/HER2-negative (ER+/HER2-) advanced breast cancer (ABC) include ET plus targeted agents (CDK4/6i or PI3K/AKT/mTOR-pathway inhibitors). Elacestrant is the first single-agent oral...

Development and internal validation of the Low Cardiac Index Score: a simplified bedside tool for continuous intraoperative screening

<title>Abstract</title> Purpose Advanced haemodynamic monitoring of cardiac index is restricted to selected high-risk cases, leaving most patients undergoing major surgery without real-time assessment. We aimed to develop and internally validate a simplified bedside score for con...

The Reverse Calcification Technique (RCT): A Quantitative Parametric Model of Aortic Stenosis Progression

Abstract Introduction Aortic stenosis (AS) develops from calcific aortic valve disease (CAVD), which narrows the aortic valve opening as leaflet stiffness increases due to calcium deposition. This study extends the Reverse Calcification Technique (RCT) by incorporating a time dim...

The “POP-IT” ear deformity: early recognition and non-surgical management of a novel neonatal auricular deformation

BACKGROUND: Congenital auricular deformities are common in newborns, yet many remain underdiagnosed despite the availability of effective early non-surgical correction. We describe a previously unreported auricular deformation, termed the "POP-IT" ear deformity, and present our e...