Quzhou City People's Hospital

Serum clusterin, neurofilament light chain, and LDL-C cholesterol for risk stratification of cognitive impairment in parkinson’s disease

Serum biomarkers, due to their advantages of easy accessibility and repeatability, show significant potential for early identification and stratification of cognitive impairment in Parkinson's disease (PD). This study aimed to systematically evaluate the expression differences of...

A multimodal Vision-Mamba model based on non-contrast CT hematoma and shell features predicts early hematoma expansion in hypertensive intracerebral hemorrhage: a multicenter study

To develop and evaluate a multimodal Vision-Mamba deep learning (DL) model integrating clinical data, noncontrast computed tomography (NCCT) hematoma features, and shell features to predict early hematoma expansion (EHE) in hypertensive intracerebral hemorrhage (HICH). In this mu...

Insulin resistance as a potential mediator between central obesity and diabetic kidney disease risk in type 2 diabetes

Abstract Obesity is a key risk factor for diabetic kidney disease (DKD). However, BMI fails to capture body fat distribution. We hypothesized that central obesity, rather than generalized obesity, is associated with DKD risk in patients with type 2 diabetes mellitus (T2DM), and t...

Latent profile analysis and associated factors of injection-related fear in school-aged children: a cross-sectional investigation

Injection-related fear in school-aged pediatric patients may influence their cooperation with medical procedures and psychological wellbeing. However, few studies have characterized distinct latent profiles of injection-related fear in this pediatric population. To further clarif...