Qiqihar Medical University

Prolonged exposure to atrazine through drinking water facilitates splenic apoptosis and induces exhaustion-like checkpoint upregulation in mice

Atrazine (ATR) is a widely used herbicide that persists in aquatic environments, raising concerns regarding its long-term immunotoxicity. As a central immune organ, the spleen represents a potential toxicological target, yet the impact of prolonged ATR ingestion via drinking wate...

TUDCA was identified as a potential therapeutic drug for nonalcoholic steatohepatitis complicated with hypercholesterolemia targeting ADRA2C by integrated bioinformatics and experimental verification

Abstract Nonalcoholic steatohepatitis (NASH) is a type of liver disease in which fat accumulates in the liver with inflammation. Hypercholesterolemia is a common autosomal dominant inherited metabolic disease. Previous studies have suggested a potential association between NASH a...

Study on the correlation between serum Th1/Th2 balance and the risk of osteoporosis in patients with helicobacter pylori infection

This study aimed to investigate the correlation between serum T helper 1/T helper 2 (Th1/Th2) balance and the risk of osteoporosis (OP) in patients with Helicobacter pylori (Hp) infection. All patients were tested for both Hp and bone mineral density (BMD). A total of 200 patient...