Pulmonary Vascular Research Institute

Systemic Hypertension and Survival in Pulmonary Hypertension

Importance Pulmonary hypertension (PH), a progressive and life-threatening condition with rising prevalence among older adults, frequently coexists with systemic hypertension, the prognostic impact of which is poorly understood. Objective To evaluate the association between syste...

B Cell Mechanisms Underlie IgG Glycan Alterations in Obesity

Abstract Insulin resistance is a major complication of obesity. In adults with obesity insulin resistance is associated with a hyposialylation of the Fc-linked glycan on IgG, and a causal link between IgG hyposialylation and glucose dysregulation has been demonstrated in obese mi...