Program for Appropriate Technology in Health

Spendworth Frontier Method

Spendworth Frontier Method 1.0 describes the public measurement and confirmation framework used to support Spendworth configuration evidence. It defines the public-facing method boundary without disclosing proprietary engine logic, private reference infrastructure, or implementat...

Spendworth Frontier Method

Spendworth Frontier Method 1.0 describes the public measurement and confirmation framework used to support Spendworth configuration evidence. It defines the public-facing method boundary without disclosing proprietary engine logic, private reference infrastructure, or implementat...

Influence of gut microbiota on immune responses and protection in volunteers receiving the live attenuated oral ETEC vaccine ACE527 followed by virulent ETEC H10407 challenge

Enterotoxigenic Escherichia coli (ETEC) remains a major cause of diarrheal morbidity with no licensed vaccines. Role of gut microbiota in vaccine immunogenicity and protection was investigated using 16 S rRNA sequencing from the stool samples of 27 volunteers receiving two doses...

Harms associated with engaging with AI for mental health support: A scoping review protocol

Background Artificial intelligence (AI) is increasingly used for mental health support, through both purpose-built products and general-purpose large language models (LLMs), at a pace far greater than evidence of their efficacy or safety. There is no consensus taxonomy of the pot...