Princess Margaret Hospital for Children

Impact of Socioeconomic Status and Rurality on the Rate of Prenatal Detection of Major and Critical Congenital Heart Disease in Western Australia

AIM: Prenatal diagnosis of congenital heart disease (CHD) is associated with reduced infant morbidity and mortality. Location and subsequent socioeconomic status influence rates and timing of prenatal diagnoses of CHD. We investigated the impact of socioeconomic status and rurali...

Implementing reproductive carrier screening to include diverse Asian populations: insights from Singapore

Abstract Background As part of Singapore’s effort towards precision medicine tailored to Asian diversity, we describe the implementation of a nationwide reproductive carrier screening program. Using a customised 112-gene panel, targeting population-specific recessive genetic dise...

Detection of viral pathogens associated with acute lower respiratory infection in children in the Eastern Highlands Province of Papua New Guinea: a matched case-control study

Introduction In Papua New Guinea, acute lower respiratory infection (ALRI) is the most common reason for childhood hospitalisation and death. Recent changes in epidemiology, diagnostic approaches and vaccine policy warrant re-examination of the aetiology of ALRI. Methods A matche...

Corticosteroid use in children with community acquired sepsis: a multicentre prospective cohort study

Objectives Corticosteroids in paediatric sepsis have the potential to improve outcomes, yet there is little supporting evidence regarding efficacy, choice of agents, dose or timing of administration. We describe the patterns of corticosteroid use in children hospitalised with sus...

Assessing the Prevalence and Impact of Allied Health Disciplines in Hospital in the Home Services: A Scoping Review

Importance Hospital in the Home (HITH) is a model that delivers inpatient-level care within the patient’s home, substituting bricks-and-mortar hospital bed occupancy and the associated costs. HITH models have rapidly expanded internationally throughout the past five years. With t...

Following the rules: which type 1 diabetes guidelines, protocols and recommendations are tertiary clinics in Australia following? A quantitative study

OBJECTIVES: This study characterises the use of type 1 diabetes (T1D) guidelines and protocols in Australian T1D clinics working with paediatric patients, and determines if management practices align with T1D-specific guidelines. METHODS: T1D clinic service leaders responded to a...

Exploration of the relationships between health literacy and experience of care integration in parents of children with special healthcare needs: a cross-sectional study

This study sought to identify health literacy profiles of Australian parents of children with special health care needs (SHCN), and explore the relationships between health literacy, experiences of health care integration, and parent stress. A cross-sectional study design was use...

Concurrent Associations Between the OMNI Rating of Perceived Exertion and Measures of Monitoring Training Load in Non-Elite Adolescent Team Sport Athletes

This study aimed to investigate associations between training load (TL) calculated using the OMNI rating of perceived exertion scale (OMNI-RPE) and heart rate (HR) and velocity-derived measures of TL in non-elite adolescent team sport athletes. Fifty-four athletes participated in...

Evaluating the Impact of Clonidine and Midazolam Premedication on Emergence Delirium in Pediatric Patients

BACKGROUND: adrenoceptor agonists, such as clonidine, have gained popularity for their sedative and analgesic properties. The effect of these agents on the incidence of emergence delirium remains uncertain. This study evaluated whether premedication with clonidine or midazolam is...