Prevention Institute

Development and internal validation of the Low Cardiac Index Score: a simplified bedside tool for continuous intraoperative screening

<title>Abstract</title> Purpose Advanced haemodynamic monitoring of cardiac index is restricted to selected high-risk cases, leaving most patients undergoing major surgery without real-time assessment. We aimed to develop and internally validate a simplified bedside score for con...

In vitro metabolic signaling in two intestinal bacterial isolates: glutamate-driven transcriptional and functional reprogramming in Clostridium butyricum and Bacteroides thetaiotaomicron

ABSTRACT Monosodium glutamate (MSG; L-glutamate monosodium salt) is among the most widely used flavor enhancers, yet its molecular effects on gut microbial physiology remain poorly understood. Here, we examined the strain-specific transcriptomic and metabolic responses of Clostri...