Presbyterian Hospital

Evaluation of Four-Factor Prothrombin Complex Concentrate Dosing for Major Bleeding Following Cardiac Surgery

Four-factor prothrombin concentrate complex (4F-PCC) may be used for significant bleeding following cardiac surgery but the optimal dosing has not been established. The purpose of this study was to compare two dosing strategies of 4F-PCC in cardiac surgery patients. This retrospe...

Parental Stigma and “Good Parenting” in Child and Adolescent Mental Health

OBJECTIVE: Parents of children with mental health problems often experience judgment about their parenting. Such stigma is associated with lower parental well-being and greater child symptom severity. Theory-driven descriptions of and interventions for parental stigma are limited...

Evaluation of a Commercial Pediatric Sepsis Early Detection Alert in the Emergency Department

Importance Screening tools have been implemented with the goal of improving early detection of pediatric sepsis, with limited evidence of effectiveness. The Epic Systems Pediatric Sepsis Early Detection Model (PESM) and its associated clinical alert have been widely implemented i...

Randomized phase II trial of liposomal cytarabine and daunorubicin with or without pomalidomide in newly diagnosed acute myeloid leukemia myelodysplasia-related

Not available.

The impact of co-occurring opioid and stimulant use disorders on unplanned readmissions among patients hospitalized with bacterial infections

Opioid and stimulant use disorders (OUD and StUD) are major drivers of injection drug use (IDU)-related bacterial infections requiring hospitalization and may increase readmission risk. However, the independent and combined effects of these factors on short-term readmission risk...

Multiligament Injury, Medial Meniscus Tear, Hyperextension‐Type Bone Bruise Pattern, and Younger Age Predict Magnetic Resonance Imaging‐Defined Tear Location in Acute, Complete Posterior Cruciate Ligament Injuries

Purpose To characterize the epidemiology of posterior cruciate ligament (PCL) tear locations and identify clinicodemographic and injury‐related predictors. Methods This retrospective cohort study at a single institution included patients with acute, complete PCL injuries between...

Establishment of Patient-Derived Xenotransplant and Cell Line Models for Canine B-Cell Lymphoma

High-grade canine B-cell lymphoma (cBCL) is a spontaneous cancer in dogs with similar pathologic features as human diffuse large B-cell lymphoma (DLBCL). The value of comparative oncology to both dogs and humans has long been recognized, but the progress in cBCL research has been...

The perils of a “hypertensive” diagnosis

The current framework for approaching patients with severe hypertension assigns every patient with arterial pressure above an arbitrary threshold to a state of either “hypertensive emergency” or “hypertensive urgency.” By labeling every condition in these patients a “hypertensive...

Colorectal cancer screening with multitarget-stool DNA testing: real-world adherence and follow-up colonoscopy in a large urban academic health system

OBJECTIVE: This real-world study evaluated adherence to multitarget-stool DNA (mt-sDNA) testing and completion of follow-up colonoscopy (FU-CY) among patients aged 45-75 years in NewYork-Presbyterian, a large urban healthcare system. METHODS: This retrospective analysis of tests...

Preoperative Visual Field Patterns Associated with Selection for Concurrent Eyelid and Brow Ptosis Repair

Introduction: Determining when to perform combined eyelid and brow surgery for functional deficits remains subjective, despite measurable visual field (VF) impairment in affected patients. Objectives: We sought to identify VF patterns associated with selection for combined eyelid...

Feasibility and Operator-Reported Utility of Transesophageal Lung Ultrasound As an Adjunct to Resuscitative Transesophageal Echocardiography in the Evaluation of Shock: A Multicenter Observational Study

Objectives: To describe the utilization, feasibility, and operator-reported diagnostic and management impact of transesophageal lung ultrasound (TELUS) integrated into resuscitative transesophageal echocardiography (TEE) for the assessment of mechanically ventilated adults with s...

Strategies To Sustain the U.S. Pediatric Anesthesiology Workforce

Pediatric anesthesiology is a deeply rewarding specialty, and the job market remains favorable for the trainees who choose it. However, the U.S. pediatric anesthesiology workforce is facing a convergence of challenges, including declining fellowship recruitment, increasing nonope...

The Global Epidemiology of Metabolic Dysfunction-Associated Steatotic Liver Disease: Regional Hotspots, Trends, and Future Projections

Purpose of Review This review highlights the global prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), assesses comparability of the former definition of non-alcoholic fatty liver disease (NAFLD)-era estimates with the 2023 steatotic liver disease (SL...

Headache Attributed to Genetic Vasculopathies

PURPOSE OF REVIEW: Headaches are a common chief complaint and a significant contributor to growing healthcare costs. Headaches are broadly categorized as primary or secondary, the latter indicating that they are a symptom of an underlying medical condition. Genetic vasculopathies...

A Multilevel Intervention to Identify Individuals for Genetic Testing and Treatment

Importance Cascade genetic testing (CGT) is a key strategy for cancer prevention in families with hereditary breast and ovarian cancer syndrome (HBOC) and Lynch syndrome (LS), yet uptake among at-risk relatives remains persistently low, particularly in medically underserved popul...

Methadone-Based Enhanced Recovery after Surgery Protocol in DIEP Flap Breast Reconstruction: A 4-Year Analysis

Background: This study evaluates the effectiveness of the New York--Presbyterian/Weill Cornell methadone-based enhanced recovery after surgery (ERAS) protocol in reducing postoperative pain and narcotic consumption in patients undergoing deep inferior epigastric perforator flap b...

A study protocol for developing an implementation strategy bundle to enhance adoption of pediatric familial hypercholesterolemia screening

Familial hypercholesterolemia (FH) is the most common primary lipid disorder of childhood, affecting 1 in 250–350 children. Universal childhood cholesterol screening is an opportunity for earlier and more effective FH diagnosis and treatment that is superior to adult screening in...

Effectiveness of RSV Prevention Strategies in US Infants: 2024–2025

OBJECTIVE: In 2023, 2 products, a long-acting monoclonal antibody (nirsevimab) and maternal respiratory syncytial virus (RSV) vaccination, were recommended in the United States to prevent severe RSV disease among infants in their first RSV season. Low uptake during the 2023 to 20...