Port Said University

Psychological well-being among institutionalized older adults: The roles of mattering, alexithymia, and spirituality

BACKGROUND: Institutionalized older adults often face emotional challenges, including a diminished sense of mattering and difficulties in identifying or expressing emotions (alexithymia), both of which can negatively affect their psychological well-being. OBJECTIVES: The study ai...

Geometry-Conditioned Conformal Calibration for Guaranteed False-Alarm Control in Uncertain Nonlinear Photovoltaic Systems

A fault detector inside an active fault-tolerant loop drives an automatic action, so every false alarm commands a reconfiguration for a fault that is absent. In a photovoltaic (PV) plant the false-alarm rate has to be controlled within each operating regime, because the healthy u...

Immune checkpoint inhibitors for African people living with HIV: T-cell exhaustion, endemic co-infections, and the oncology trial gap

Immune checkpoint inhibitors (ICIs) have fundamentally transformed modern oncology by unleashing the body’s anti-tumor immunity, yet people living with HIV (PLWH) were systematically excluded from the pivotal registration trials. This evidence gap is especially consequential in s...

A New Current Fingerprinting Sensing Method for Adaptive Protection of PV-Integrated Distribution Networks

Grid-following photovoltaic (PV) inverters inject fault currents whose magnitude and phase are set by the control mode active during the disturbance, so directional overcurrent relay (DOCR) settings coordinated for one inverter response can miscoordinate after a mode change. This...

Comparative analysis of 3D printing technology and conventional construction methods in construction practices: a case study based on biomimetic design and AI-generated form-finding

Abstract Recently, 3D printing has emerged as a groundbreaking fabrication technology, enabling the precise fabrication of complex structures directly from digital models. Despite its potential, integrating 3D printing into architectural design and construction practices remains...

Comparative effectiveness of statins, metformin, and vitamin D, for prevention of preeclampsia: a systematic review and network meta-analysis of randomized trials

Abstract Background Preeclampsia is a leading cause of maternal and neonatal morbidity and mortality worldwide, yet effective pharmacological preventive strategies remain uncertain. Statins, metformin, and vitamin D, alone or combined with omega-3, have been investigated for pote...

Hibiscus sabdariffa protects against fibromyalgia by modulating the neuroinflammation–oxidative stress–microRNA axis

Fibromyalgia (FM) is a chronic syndrome characterized by widespread pain, fatigue, cognitive dysfunction and neuropsychiatric disturbances, associated with dysregulated oxidative stress and neuroinflammation. Emerging evidence suggests that microRNAs guiding these pathways, inclu...

A novel real-time integrated adaptive stable offloading (RIASO) algorithm in multi-access edge computing

Abstract Mobile Edge Computing (MEC) and Mobile Computation Offloading (MCO) help IoT devices with limited computational capabilities and battery by offloading tasks to the nearest resource-rich servers in MEC. Deciding to execute the tasks at the user device or the edge server c...

Cardiovascular and functional outcomes of glucagon-like peptide−1 receptor agonists in heart failure with preserved or mildly reduced ejection fraction: a systematic review and meta-analysis of randomized controlled trials

Heart failure with preserved (HFpEF) or mildly reduced ejection fraction (HFmrEF) accounts for more than half of heart failure (HF) cases and is strongly associated with obesity and metabolic dysfunction. Glucagon-like peptide−1 receptor agonists (GLP-1RA) provide cardiometabolic...

Mangrove reproductive dynamics and the role of honeybee introduction in the vulnerable ecosystems of the Northwestern Arabian Peninsula

Abstract Mangrove forests are increasingly threatened worldwide and a growing number of regeneration initiatives have surged, aimed at reversing their decline. A critical factor influencing the effectiveness of these efforts is the reproductive success of mangrove plants. In this...

GL-TGS: Guarded Learning-Based Time-Gap Supervision for Adaptive MPC in Perception-in-the-Loop Autonomous Highway Driving

Adaptive cruise control (ACC) tracks a time-gap reference that trades efficiency against spacing safety; in practice this gap is fixed offline, although the safest choice depends on the closing speed and on the reliability of the perception that supplies the lead-vehicle state. W...

Protective effect of Dapagliflozin on hepatic encephalopathy induced by thioacetamide in rats: involvement of ERK, JNK, and Nrf2/HO-1 pathways

Hepatic encephalopathy (HE) is a neuropsychiatric disorder associated with oxidative stress, neuroinflammation, and hyperammonaemia secondary to hepatic dysfunction. This study aimed to investigate dapagliflozin's effects (DAPA) against HE induced by thioacetamide (TAA) in rats a...

Evaluation of sirtuin 1 serum level and gene expression in patients with metabolic syndrome accompanied by metabolic dysfunction-associated steatotic liver disease

Abstract Background Metabolic syndrome is a cluster of conditions, including abdominal obesity, dyslipidemia, hypertension, and impaired glucose metabolism, that significantly increase the risk of cardiovascular disease and type 2 diabetes mellitus (T2DM). Metabolic dysfunction-a...

Beclin-1 and HIF-1α immunohistochemical expression in breast carcinoma: insights into tumor biology

Breast carcinoma is a biologically heterogeneous disease in which tumor behavior and clinical outcome are influenced by multiple cellular pathways, including autophagy and hypoxia. Beclin-1, a key autophagy-related protein, and hypoxia-inducible factor-1α (HIF-1α), a central regu...