Pontifical Catholic University of Puerto Rico

DNA methylation modulation by 5-Azacytidine regulates EMT markers and reduces invasiveness in docetaxel-resistant prostate cancer cells

<title>Abstract</title> <bold>Background:</bold> Metastatic castration-resistant prostate cancer (mCRPC) is associated with poor prognosis and high mortality, largely due to the emergence of androgen and chemotherapy resistance. Resistance to docetaxel occurs in nearly 50% of pat...