Polish Mother’s Memorial Hospital Research Institute

Explained and Residual Variability of the Fetal Mechanical PR Interval in Structurally Normal Hearts: A Secondary Analysis of Physiological, Biometric, and Doppler Covariates

Background/Objectives: A previous publication reported that routinely measured covariates explained approximately 10% of fetal mechanical PR interval (mPR) variance. This secondary analysis examined how explanatory information is distributed among correlated predictors, their inc...

Empirical Antibiotic Initiation for Suspected Early-Onset Neonatal Infection in the Setting of Maternal GBS Screening and Intrapartum Antibiotic Prophylaxis: A Single-Center Retrospective Cohort Study

Background and Objectives: Maternal Group B Streptococcus (GBS) screening and intrapartum antibiotic prophylaxis have reduced early-onset GBS disease. However, suspected early-onset neonatal infection (EONI) remains a broader clinical challenge, as signs prompting empirical antib...

RED-S IN ENDURANCE ATHLETES — SKELETAL CONSEQUENCES OF CHRONIC LOW ENERGY AVAILABILITY

Background. Relative Energy Deficiency in Sport (RED-S) is an increasingly recognized health problem among endurance athletes. The main mechanism leading to the development of RED-S is low energy availability (LEA), resulting from insufficient energy intake in relation to exercis...

Home-based simeox therapy and respiratory symptoms in Non-CF bronchiectasis: a randomized pilot study

Abstract Airway clearance is a cornerstone of management in non–cystic fibrosis bronchiectasis (NCFB), a chronic condition characterized by airway inflammation, mucus hypersecretion, and impaired mucociliary clearance, leading to recurrent infections and progressive lung function...

General Assessment of Indole Derivatives and Wnt Pathway as Potential Key Factors Against Various Diseases, with Particular Emphasis on Thyroid Tumors

Indoles are chemical compounds that naturally occur in Prokaryotes and Eukaryotes. For example, indole alkaloids mainly occur in plant families such as Nyssaceae, Rubiaceae, Apocynaceae, and Loganiaceae. The popularity of indoles has led to further research into their function an...