Pirogov Russian National Research Medical University

Ring Contractionof Bicyclic Lactams: A MolecularEditing Aza-Favorski-Type Approach to Tetrahydroquinoline-2-carboxylicAcids

Abstract Development of skeletal editing methods offers new horizons for the acceleration of drug discovery. An original aza-Favorski-type approach is described for the ring contraction of benzazepine-2-ones, providing versatile tetrahydroquinoline-2-carboxylic acids. The sequenc...

Results of the meeting of the Interdisciplinary Expert Council on an integrated approach to the management of peri- and postmenopausal women with psycho-emotional and neurological disorders

The reduction in sex hormone levels during the menopausal period substantially impacts patients' quality of life and serves as a significant risk factor for psycho-emotional disorders. Current clinical guidelines from both Russian and international sources recognize menopausal ho...

Results of the meeting of the Interdisciplinary Expert Council on an integrated approach to the management of peri- and postmenopausal women with psycho-emotional and neurological disorders

The reduction in sex hormone levels during the menopausal period substantially impacts patients’ quality of life and serves as a significant risk factor for psycho-emotional disorders. Current clinical guidelines from both Russian and international sources recognize menopausal ho...