Physics of Life

High-content image-based screening reveals vaccinia virus membrane proteins as potential regulators of LC3 lipidation

Autophagy is a catabolic process used for the degradation of organelles and proteins, and it also functions as a cellular defense mechanism, known as xenophagy, during infection. Vaccinia virus (VACV), the prototypic poxvirus, replicates exclusively in the cytoplasm of host cells...

Self-organization of vascularized muscle from bovine embryonic stem cells

Abstract Cultured beef offers a promising alternative to traditional meat. While adult stem cells are commonly used as the cell source for cultured beef, their proliferation and differentiation capacities are limited. Current manufacturing processes for cultured beef steaks often...