Pharmo Institute

Associations of frailty and COVID-19 severity with long-term health outcomes of COVID-19 among older people

To investigate whether frailty and COVID-19 severity are associated with long-term health outcomes of COVID-19 in older people. In this cohort study, older people aged ≥ 70 years with COVID-19 between January 2020 and December 2021 were invited for follow-up. Participants were re...

Co-Encapsulation and In Vitro Gastrointestinal Release of Gallic Acid and Curcumin: A Comparison between Double Emulsions and Templated Core-Laden Bubble Systems

Abstract This study examines how the intermediate phase in hierarchical colloidal carriers influences the co-encapsulation and in vitro gastrointestinal release of hydrophilic gallic acid and hydrophobic curcumin, using double emulsions (DE; W1/O/W2) and templated core-laden bubb...

SOLiD‐MaP: A Photoproximity Labeling Platform for Small Molecule Binding Site Mapping on RNA

RNA-targeting small molecules are emerging as promising therapeutic modalities, but their development requires methods that define binding sites and evaluate RNA target selectivity. Existing approaches for detecting ligand-RNA interactions have provided powerful foundations, yet...