People's Liberation Army No. 150 Hospital

BTSR-Net: Boundary–topology guided structural refinement for high-resolution remote sensing image segmentation

Semantic segmentation of high-resolution remote sensing imagery in complex urban scenes often suffers from insufficient modeling of boundary neighborhoods, causing ambiguity near class interfaces and weakening the continuity of elongated structures. To address this issue, we prop...

Urine metabolomics reveals key pathways supporting neuronal regeneration and consciousness recovery in disorders of consciousness

Disorders of consciousness (DoC) are debilitating conditions resulting from severe brain injury, requiring not only structural preservation but also active neuronal regeneration for recovery. These regenerative processes are metabolically demanding and can be tracked through syst...

Global genomic epidemiology and antimicrobial resistance dynamics of Pasteurella multocida

Abstract Pasteurella multocida ( P. multocida ) is a crucial zoonotic pathogen, and its severe prevalence of antimicrobial resistance has attracted widespread attention in recent years. A global genomic analysis of 1,875 P. multocida isolates collected from 35 countries between 2...

Topiramate use for maintenance antiseizure therapy in children with hematologic malignancies experiencing posterior reversible encephalopathy syndrome during chemotherapy: a single-center retrospective study

Seizures are a predominant symptom in posterior reversible encephalopathy syndrome (PRES) occurring in the context of chemotherapy. However, anti-seizure medications (ASMs) selection remains challenging due to potential pharmacokinetic interactions with chemotherapeutic agents. T...

Indole-3-propionic acid is an endogenic agonist of hypoxia-inducible factor-1α to protect the heart against hypoxia

Abstract Tryptophan catabolism by the gut microbiota is increasingly recognized as a hub connecting environmental challenges to cardiovascular health. By systematically profiling tryptophan metabolites in humans who had moved from low altitude to an altitude of 4300 m and in mice...

Merging artificial intelligence and retinal vascular geometric parameters: A novel tool for diagnosis and prognosis prediction of diabetic nephropathy

Abstract Background: Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. The retinal microvasculature, as the only directly observable microvasculature, may reflect DN progression. This study aims to construct a non-invasive diagnostic and prognostic predic...

Fixation efficacy of a sliding cannulated screw system for unstable Pauwels type III femoral neck fractures: a finite element analysis, biomechanical investigation, and clinical study

Abstract Objective To compare the finite element performance, biomechanical properties, and short-term clinical outcomes of a novel Sliding Cannulated Screw System (SCSS) versus conventional Three Cannulated Screws (3CS) for unstable Pauwels type Ⅲ femoral neck fractures, and to...

The impact of preoperative radiological paraspinal lumbar measures on the postoperative satisfaction of patients following lumbar fusion surgery– a retrospective case-control study

Paraspinal muscles have been reported to associated with postoperative outcomes in patients undergoing lumbar spine surgery. This study aimed to determine whether preoperative radiological measures of lumbar paraspinal muscles could predict postoperative patient satisfaction. A t...