People's Hospital of Yangzhong

FGF-23 is associated with increased risk of abdominal aortic calcification

Fibroblast growth factor 23 (FGF23) is involved in the regulation of phosphate metabolism and has been linked to vascular calcification. However, the genetic association between FGF23 and abdominal aortic calcification (AAC) remains unclear. We conducted a bidirectional two-sampl...

Contrast-enhanced sonography in the diagnosis of Langerhans cell hyperplasia in children with isolated liver involvement

Rationale: Isolated hepatic involvement of Langerhans cell histiocytosis (LCH) in the pediatric population is an exceedingly rare condition. Its clinical presentation is nonspecific, and its imaging features frequently overlap with those of other hepatic focal lesions, rendering...

Mutations in EnvZ, KPC, and OmpK36 contribute to the evolution from ceftazidime-avibactam heteroresistance to stable resistance in carbapenem-resistant Klebsiella pneumoniae

Antibiotic heteroresistance, an unstable phenotype wherein a minority-resistant subpopulation coexists with a majority-susceptible population, can evolve to stable resistance following in vivo antibiotic exposure, thereby substantially increasing the risk of treatment failure. Ho...

Yield-point detection can improve the mechanical performance of cancellous bone screws

Appropriate torque applied to screws is an insurance for strong and durable fracture fixation. We compared the mechanical characteristics of four types of bone screws during insertion to facilitate the development of an optimal screw torquing strategy. Bone screws were inserted i...