Peoples' Friendship University of Russia

Leber’s hereditary optic nerve atrophy

This review is devoted to Leber’s hereditary optic neuropathy (LHON), a rare maternally inherited ophthalmic disorder presenting as optic nerve atrophy and associated with an unfavorable prognosis. LHON is the most common primary mitochondrial DNA disorder, and most patients (mor...

Prognostic impact of upper urinary tract drainage in obstructive renal failure related to cervical cancer in Guinea: drainage failure as a poor prognostic factor

Abstract Introduction The impact of upper urinary tract drainage on survival in patients with cervical cancer complicated by obstructive renal failure remains controversial. The objective of this study was to evaluate the prognostic impact of upper urinary tract drainage on overa...

Non-Random Association of Ultraconserved Genomic Elements (UCE) with Human Genes

Ultraconserved elements (UCEs) are among the most evolutionarily conserved DNA sequences in vertebrate genomes, yet the biological mechanisms underlying their extraordinary conservation remain poorly understood. Using the recently developed dedUCE database comprising 12,813 human...

Linker Engineering of Hybrid Triazole-Thiazolidine Antifungals Identifies a Promising Lead Against Drug-Resistant Candida Species

Background: The emergence of antifungal resistance and the limited number of clinically available antifungal drug classes necessitate the development of new agents with improved efficacy and safety. We investigated how linker architecture influences the antifungal activity and le...

Multivariate characterization of foliar morpho-anatomical traits supporting adaptive trends and taxonomic resolution in halophytic grasses

Leaf morphology and epidermal traits of 15 salt-tolerant grasses belonging to 10 genera from the Bahadur Khel Salt Range were examined using a microscopic technique for the first time. Eight qualitative characters (epidermal cell shape, anticlinal wall patterns, type of stomata a...

A Modified Constrained Groove Pressing Process (MCGP) for Enhanced Strength and Microstructural Refinement of Deoxidized High-Phosphorus (DHP) Copper Sheets: Potential Implications for Marine Component Reliability

Deoxidized high-phosphorus (DHP) copper is widely used in marine heat-exchangers and seawater piping, where long-term structural reliability demands both high strength and a deformation-tolerant microstructure to resist damage initiation. Constrained groove pressing (CGP) is a sc...

AI-driven ESG analytics for economic resilience: a hybrid ACO-CNRC framework for risk and performance prediction in emerging economies

Environmental, Social, and Governance (ESG) practices are increasingly used to quantify sustainable corporate behavior and are often linked to long-term financial performance and resilience in public equity markets. This study proposes an AI-based predictive framework to analyze...