People 's Hospital of Jilin Province

Dynamic Changes in Serum Glial Fibrillary Acidic Protein Levels Predicts Early Neurological Deterioration After Intravenous Thrombolysis in Minor Stroke

ABSTRACT Objective Minor strokes may be associated with early neurological deterioration (END) and disabilities. The objective was to investigate the role of serum glial fibrillary acidic protein (GFAP) levels in predicting END. Methods Data originated from a multicenter cohort s...

Breaking the Lipid Bottleneck: A Mitophagy‐Driven Nanoregulator Amplifies Ferroptosis for Colorectal Cancer Immunotherapy

ABSTRACT Colorectal cancer (CRC) therapy is severely constrained by the immunosuppressive tumor microenvironment (TME). This study presents a TME‐responsive nanometabolic regulator, ZnO 2 @Fe@HA (ZFH), designed to bridge mitochondrial dysfunction, lipid reprogramming, and ferropt...

Early renal perfusion phenotypes and renal recovery in critically ill patients with or at risk for acute kidney injury: a prospective multicenter cohort study

BACKGROUND: Acute kidney injury (AKI) in critical illness is heterogeneous, and conventional Kidney Disease: Improving Global Outcomes (KDIGO) classification may not capture early physiologic differences relevant to renal recovery. METHODS: Critically ill adults with or at risk f...

Sitting Time and Physical Activity Correlate With Asthma Exacerbations in Adults: A Cross‐Sectional Study From the Australasian Severe Asthma Network

Summary Lower levels of sitting time were associated with a lower risk of severe asthma exacerbations in adults. High levels of physical activity eliminated the detrimental association of sitting time with severe asthma exacerbations in adults.