Pelita Harapan University

Radiologic phenotyping of two PIK3CA-related overgrowth spectrum cases: distinguishing FAO and CLOVES syndrome

Abstract Background PIK3CA-related overgrowth spectrum (PROS) comprises a heterogeneous group of mosaic disorders characterized by segmental overgrowth and vascular anomalies. Although genetic confirmation is considered the diagnostic gold standard, it is often limited by mosaici...

Cultivating national solidarity: An action research study among christian generation Z students in Indonesia

Indonesia’s national motto, “Bhinneka Tunggal Ika” (Unity in Diversity), faces contemporary challenges in fostering genuine social cohesion. This study investigates whether a theologically-grounded educational intervention can enhance inclusive national solidarity among Christian...

The impact of professional competencies and cultural legacy on medical leadership competencies with leadership style as a mediating variable

This study examines the influence of professional competencies and cultural legacy on medical leadership competencies, with leadership style as a mediating mechanism in a teaching hospital in Indonesia. A quantitative cross sectional design was used, with survey data collected fr...

Preoperative global longitudinal strain predicts myocardial hypertrophy burden but not the magnitude of reverse remodeling after surgical aortic valve replacement in severe aortic stenosis

Abstract Background Global longitudinal strain (GLS) is a marker of subclinical myocardial dysfunction and predicts adverse outcomes in severe aortic stenosis. However, its ability to predict the magnitude of left ventricular (LV) reverse remodeling following surgical aortic valv...

The molecular spectrum of alpha- and beta-thalassemia pathogenic variants in Indonesia: implications for national screening and prevention

Abstract Background Thalassemia is classified globally as a rare disease; however, it represents a major public health burden in many low‑ and middle‑income countries due to its high prevalence and limited access to care. In Indonesia, one of the world’s most genetically diverse...

A Psychological Exploration of Help-Seeking in Intimate Partner Violence: Findings From a Scoping Review

Researchers in various countries have identified that intimate partner violence affects victims of all ages. The process of psychological recovery from experiences of intimate partner violence must commence with the victim seeking help. The present review was conducted in accorda...

Chronic Venous Insufficiency in Women: Hormonal and Gender Differences

Abstract Chronic venous insufficiency (CVI) represents a significant global health burden with marked gender disparities in prevalence, presentation, and pathophysiology. This comprehensive review examines the multifaceted impact of hormonal and gender-specific factors on CVI dev...

Cleft Alveolar Bone Grafting Using Mandibular Symphyseal Bone Graft and Resorbable Collagen Membrane: A CBCT-Based 3-Dimensional Morphometric Analysis

Objective Iliac cancellous bone graft has been regarded as the gold standard for secondary alveolar bone grafting (SABG); however, it is associated with a high resorption rate and donor-site morbidity. This study aimed to evaluate the radiographic outcomes of SABG using a mandibu...