Pediatric Oncology Group

Children With Synpolydactyly Type I Homozygous HOXD13 Mutations: Embryology and Surgical Correction of the “Cupping” of the Hands and Feet

PURPOSE: Some patients with familial Synpolydactyly Type I have severe flexion deformities of the hands and feet at the metacarpophalangeal and the metatarsophalangeal joints, and the resulting deformity has been named "cupping" of the hands and feet. Severe "cupping" requiring s...