Pázmány Péter Catholic University

From timekeeping to divisions—Molecular links between circadian rhythms and cell cycle

Circadian rhythms and the cell cycle are two fundamental biological oscillators. They are linked through molecular mechanisms creating coupled oscillators where the outcomes of this coupling depend on numerous factors, such as the directionality of coupling (i.e., unidirectional...

Complex effects of sex reversal on reproductive success in wild frogs

Sex reversal, when the environment overrides genotypic sex determination, may hasten or delay climate-driven extinction in ectothermic animals, depending on sex-reversed individuals’ reproductive ability and offspring viability. Empirically, next to nothing is known about these t...

The Global Mode of Experience in Psychodynamic Movement and Dance Therapy - Bodily Awareness as a Therapeutic Factor: Effects and Clinical Considerations.

Bodily awareness has become a central therapeutic factor in psychodynamic and body-oriented psychotherapies, yet its clinical effects and theoretical status remain insufficiently integrated. This paper offers a clinically grounded account of bodily awareness work in Psychodynamic Mov...

Transcriptome profiling of human hypothalamic agouti-related protein and proopiomelanocortin neurons regulating energy homeostasis

Abstract We present and validate a pioneering ‘IHC/LCM-Seq’ method for transcriptome profiling of spatially defined neuronal cell types detected with immunohistochemistry in sections of formaldehyde-fixed human brains. Application of IHC/LCM-Seq to male human hypothalami enables...

Inscription of Quasi-Sinusoidal Surface Relief Optical Gratings in ZEONOR™ Cyclic Olefin Polymer by a 10.5 MeV N4+ Ion Microbeam at Low Implanted Fluences

Direct writing of microstructures in ZEONOR™ cyclic olefin polymer, using a high-energy medium-mass ion microbeam, was proposed and demonstrated. Microbeams of 10.5 MeV N4+ ions were used. The implanted fluences were between 2.5·1012 and 2.0·1013 ion/cm2. The microstructures were...