Pázmány Péter Catholic University

Transcriptome profiling of human hypothalamic agouti-related protein and proopiomelanocortin neurons regulating energy homeostasis

Abstract We present and validate a pioneering ‘IHC/LCM-Seq’ method for transcriptome profiling of spatially defined neuronal cell types detected with immunohistochemistry in sections of formaldehyde-fixed human brains. Application of IHC/LCM-Seq to male human hypothalami enables...

Inscription of Quasi-Sinusoidal Surface Relief Optical Gratings in ZEONOR™ Cyclic Olefin Polymer by a 10.5 MeV N4+ Ion Microbeam at Low Implanted Fluences

Direct writing of microstructures in ZEONOR™ cyclic olefin polymer, using a high-energy medium-mass ion microbeam, was proposed and demonstrated. Microbeams of 10.5 MeV N4+ ions were used. The implanted fluences were between 2.5·1012 and 2.0·1013 ion/cm2. The microstructures were...