Pathwest Laboratory Medicine

First Serological Evidence of Exposure to Japanese Encephalitis Virus in Feral Pigs and Sentinel Chickens in Western Australia

Japanese encephalitis virus (JEV) emerged across mainland Australia in 2022, causing substantial impacts on public health and the pig industry. Its emergence raised concerns regarding potential spread into Western Australia (WA). This study aimed to determine JEV activity in WA w...

Detection of viral pathogens associated with acute lower respiratory infection in children in the Eastern Highlands Province of Papua New Guinea: a matched case-control study

Introduction In Papua New Guinea, acute lower respiratory infection (ALRI) is the most common reason for childhood hospitalisation and death. Recent changes in epidemiology, diagnostic approaches and vaccine policy warrant re-examination of the aetiology of ALRI. Methods A matche...

Integration of lipidomic and polygenic risk scores within contemporary clinical cardiovascular risk assessment pathways: a multi-cohort development and validation study

Background Guideline-recommended clinical risk scores such as AusCVDRisk underestimate cardiovascular disease (CVD) risk in a substantial proportion of individuals who later experience events, with up to 65% initially classified as low or intermediate risk. This limitation is mos...