Paraza Pharma (Canada)

A Nickel Pre-Catalyst for the O -Arylation of Primary, Secondary, and Tertiary Alcohols with (Hetero)aryl Chlorides

Abstract While base metal-catalyzed cross-couplings of alcohols and (hetero)aryl chlorides have emerged over the past decade, the development of a single pre-catalyst capable of promoting such transformations spanning all of primary, secondary, and tertiary (aliphatic) alcohols r...