Papageorgiou General Hospital

Parental stress, coping, and depressive symptoms among parents of preterm infants hospitalised in a Greek neonatal intensive care unit: A cross-sectional study

Purpose To examine NICU-related parental stress, coping strategies, and depressive symptoms in a single-centre, cross-sectional study of parents of preterm infants in a tertiary NICU in Greece. Principal results Thirty-four parents from 18 families participated. NICU-related stre...

Integrated Molecular, Clinicopathological and Immune Profiling of Non-Small Cell Lung Cancer: The MONREPOS Hellenic Cooperative Oncology Group (HeCOG) Study (HE_2TR/13)

Integrated assessment of tumour genomics and immune biomarkers may improve prognostic stratification in non-small cell lung cancer (NSCLC). We examined the distribution and prognostic relevance of somatic pathogenic/likely pathogenic variants (PVs), somatic copy-number alteration...

Infections and Anti-N-Methyl-D-Aspartate Receptor Encephalitis in Children and Adolescents: A Scoping Review of Evidence Since the COVID-19 Pandemic

Background/Objectives: Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a common autoimmune encephalitis affecting children and adolescents. Its development has been associated with preceding or concomitant infections, particularly herpes simplex virus type 1 (HSV-...

Leadership and Organizational Responses After Patient Safety Incidents: A Systematic Review of Second-Victim Outcomes and Evidence Gaps in Safety Behaviors

Background/Objectives: Patient safety incidents can adversely affect healthcare professionals, but relationships between leadership and organizational responses, clinician recovery, professional consequences, and safety-related outcomes remain incompletely synthesized. This revie...

Adjunctive Treatments for Patients with Type 1 Diabetes Using Automated Insulin Delivery Systems. A Narrative Review

Automated Insulin Delivery (AID) systems represent the most effective and safe treatment for the management of type 1 diabetes (T1D). Antidiabetic agents used for the treatment of type 2 diabetes, such as the Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists (RAs), the dual Gluco...

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activatio...

Hormone therapy ( HT ) in women with premature ovarian insufficiency or early menopause: Time to think of a new paradigm for healthy aging. A joint FIGO and IMS position paper

Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an...

Obtaining a Diagnostic Yield via Scan findings prior to the introduction of SEquencing retrospectivelY ( ODYSSEY ): a cohort study

ABSTRACT Objective To determine the retrospective yield of prenatal exome sequencing (PES) by establishing the proportion of children with a postnatal monogenic diagnosis that could have been diagnosed prenatally if PES had been available. Methods The study cohort comprised a sam...

Patterns and phenotypes of enhanced recovery after surgery implementation in gynaecological oncology: A latent class analysis

Objective: Enhanced recovery after surgery protocols are widely recommended, yet their real-world implementation remains inconsistent due to multiple barriers. This study aimed to characterise implementation patterns during early enhanced recovery after surgery adoption. Methods:...