Pacific Dental College and Hospital

Neurobehavioral Evaluation of Renin-Angiotensin System Modulators in an MPTP-Induced Model of Parkinson’s Disease in Swiss Albino Mice

BACKGROUND: Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor and nonmotor deficits. Emerging evidence suggests a role of the renin-angiotensin system (RAS) in neurodegeneration, making it a potential therapeutic target. AIM: To evaluate...

Liposomal Delivery Systems for Berberine: Formulation Strategies, Pharmacokinetic Enhancement, and Therapeutic Applications

Abstract:Berberine (BBR) is a plant-derived isoquinoline alkaloid with a remarkably broadpharmacological profile spanning antidiabetic, hypolipidemic, antitumor, antimicrobial, antiviral,and anti-inflammatory activities. Despite this therapeutic promise, its clinical utility is s...