Ottawa University

Altered sperm DNA methylation provides an epigenetic route from overweight and older men to intergenerational disease transmission

The occurrence of childhood neurodevelopmental disorders has been steadily increasing for decades, yet we have little understanding of modes of inheritance implicated in these diseases. Epidemiology studies have revealed an association between an elevated paternal Body Mass Index...

The human gut microbiome primes fever after vaccination

Fever is a common adverse reaction to vaccination, contributing to vaccine hesitancy and reduced uptake. To understand variation in fever risk, we longitudinally profiled fecal microbiota, oral temperature, and serological markers in 171 healthy adults receiving Severe acute resp...

The role of personality traits in arbitral decision-making

Purpose This study examines the relationship between arbitrators’ personality traits and three dimensions of arbitral decision-making: perceptions of decision bias, arbitral preferences, and preferred sources of decision-making. Design/methodology/approach A quantitative, deducti...

Versatile Thin Polymer Fibers Produced by a Cotton-Candy Melt-Spinning Method: Examples of Dye Doping and Microplastic Generation

Abstract We report a method for producing thin plastic fibers (TPFs) in a few minutes using an inexpensive cotton-candy machine. Commercially available plastics (PP, PMMA, PETG, and PLA) were used to evaluate the versatility of this simple technique. Thin fibers are generated sta...

Critical antecedents for successful labor-management partnerships (LMP): taxonomy, levels and the “black boxes”

Purpose Employment relations studies have examined the notion and practice of labor-management partnership (LMP); yet, a delineation of overarching explanations for successful LMP remain outstanding. This study sought to identify and classify critical antecedents for successful L...

Emerging Post‐CMOS Hardware Neurons for Brain‐Inspired Computing: Devices, Circuits, and System Integration

ABSTRACT The fundamental energy and latency limitations of the von Neumann architecture have necessitated a paradigm shift toward neuromorphic systems. This approach addresses the “memory wall” bottleneck by emulating the brain's event‐driven and massively parallel processing cap...

Resynchronisation of the Biological Clock Using Exposure to Low Oxygen Levels in Humans: An Exploratory Study

Exposure to reduced oxygen levels occurs in several real-world contexts, such as during air travel or altitude exposure, and emerging evidence suggests that hypoxia may interact with molecular pathways involved in circadian regulation. This exploratory study investigated the effe...

Hospitalization of Children in Foster Homes: A Canadian Cohort Study

BACKGROUND AND OBJECTIVES: In Canada, approximately 4% to 7% of children live in a foster home during their childhood. This study reports on hospitalizations of children in foster homes, with the hypothesis that rates of hospitalization are higher for children with foster home ex...

Laser Printing of Plasmonic Color Images in Polymer-Embedded Nanorod Films

Nanoscale structures that support surface plasmons have been used extensively to create colorful images at the surface of materials. Approaches used include dispersion of nanoparticles, the dewetting of thin films, e-beam lithography to precisely control the size and distribution...

Solving problems increases provisioning efficiency, enhancing reproductive success in male great tits

Abstract The ecological and selective processes acting on cognitive traits have received recent attention because of the potentially key role of cognition in rapid behavioural adjustments in response to environmental variation. Innovation, a cognitive process involved in the deve...

Exploring Training Needs to Facilitate Shared Decision Making in Juvenile Idiopathic Arthritis Symptom Management and the Use of the JIA Option Map

Objectives Our team developed the JIA Option Map, a web-based patient decision aid (PDA) designed to support shared decision-making (SDM) for juvenile idiopathic arthritis (JIA) symptom management. Since training for health care providers (HCP) can enhance SDM and the use of PDAs...

Performance of the 2025 ASAS-Spartan Revised Classification Criteria for Axial Spondyloarthritis in a Canadian Multicenter Inception Cohort with Psoriasis, Uveitis, or Colitis Presenting with Undiagnosed Back Pain

Objectives To test the performance of the 2025 ASAS-SPARTAN Revised Classification Criteria for Axial Spondyloarthritis (axSpA)[1] in a multicenter inception cohort of patients with undiagnosed chronic back pain attending dermatology, ophthalmology, and gastroenterology clinics w...

Exploring Decisional Factors to Include Approaches in a Patient Decision Aid for Juvenile Idiopathic Arthritis Symptom Management

Objectives Youth with juvenile idiopathic arthritis (JIA) experience physical and mental health symptoms that negatively impact their participation in daily life activities. The JIA Option Map is a web-based patient decision aid (PDA) created to facilitate decision-making for JIA...

Defining Difficult-to-Treat Rheumatoid Arthritis in Routine Care: Comparative Performance of Published Criteria and Description of Early and Late D2T-RA Phenotypes

Objectives Despite advances in treat-to-target strategies, a subset of rheumatoid arthritis (RA) patients remains refractory to therapy, described as difficult-to-treat RA (D2T-RA). The European Alliance of Associations for Rheumatology (EULAR) has proposed formal criteria for D2...