Otsu Municipal Hospital

Longitudinal Changes in the Blood Urea Nitrogen-to-Creatinine Ratio After Initiation of Abemaciclib: A Single-Center Retrospective Observational Study

Serum creatinine (Cr) elevation is frequently observed after the initiation of abemaciclib treatment. Because abemaciclib inhibits tubular creatinine secretion, Cr may increase without a true decline in glomerular filtration rate. In Japan, cystatin C is not routinely measured in...