Ospedali Riuniti Umberto I

Safety and Efficacy of Left Atrial Ablation After Percutaneous Left Atrial Appendage Occlusion in High-Bleeding-Risk Patients with Atrial Fibrillation: A Multicenter Analysis from the PROCEED-AF Ablation Registry

BACKGROUND AND AIMS: Patients with left atrial appendage (LAAO) devices are increasingly referred for AF ablation, yet anticoagulation strategies remain uncertain. The goal of this study was to evaluate the safety and efficacy of catheter ablation for atrial fibrillation (AF) in...

In‐Vivo Frame Dynamicity of Self‐Expanding Transcatheter Aortic Valves

BACKGROUND: Due to nitinol stent properties, self-expanding transcatheter heart valves (THVs) have the potential to adapt their frames to native annular dimension excursions during the cardiac cycle and therefore to maintain the physiological relevance of this behaviour. AIMS: To...

Combined Botulinum Toxin Type A and Hyaluronic Acid Versus Exclusive Hyaluronic Acid Injections: A Potential Nonsurgical Alternative for Chin Augmentation

Nonsurgical chin augmentation with hyaluronic acid (HA) fillers is a widely used technique in aesthetic medicine. However, outcomes may be influenced by hyperactivity of the mentalis muscle, which may lead to reduced longevity. Botulinum toxin type A (BoNT-A) may improve filler i...

Scientific Clinical Trial Publication Productivity in Medical Oncology: A Comparative Analysis and Data Review of Northern and Southern Italy

Background: Italy exhibits a socioeconomic divide between its northern and southern regions, which extends into healthcare delivery and biomedical research. Medical oncology is particularly affected by this structural imbalance. This paper examines geographic disparities in clini...

Continuous Glucose Monitoring and Automated Insulin Delivery in Infants with Type 1 Diabetes: Real-World Evidence to Support Future International Guidelines

To evaluate efficacy and safety of continuous glucose monitoring (CGM) and automated insulin delivery (AID) in infants. A retrospective multicenter study (13 centers) of 76 children diagnosed with antibody-positive type 1 diabetes before age 2. Outcomes at 12 months were compared...

Personalized Medicine for the Management of Non-Communicable Diseases (NCDs)

Non-communicable diseases (NCDs) are the leading cause of death worldwide and are among the major drivers of healthcare expenditure, particularly in societies undergoing progressive population aging [...]

Comparative Efficacy Of Different Computer-Aided Detection Products in Colonoscopy: A Network Meta-Analysis Of Randomized Controlled Trials.

Background and aims: Multiple computer-aided detection (CADe) systems have been developed to improve adenoma detection during colonoscopy, but their comparative efficacy and consistency of effect remain uncertain. This network meta-analysis aimed to compare the efficacy of differ...