Osaka National Hospital

Validity of Bone Mineral Density Measurements Using SONIALVISION G4: A Quantitative CT-based Evaluation

Abstract Introduction SONIALVISION G4 is a fluoroscopic imaging system equipped with a bone densitometry function calibrated against GE Healthcare dual-energy X-ray absorptiometry (DXA) measurements. However, evidence supporting the validity of in vivo bone mineral density (BMD)...

Left Atrial Voltage Attenuation Beyond Ablation Sites After Unipolar Pulsed‐Field Ablation for Atrial Fibrillation

ABSTRACT Introduction Unlike most pulsed‐field ablation (PFA) systems, Affera (Medtronic) delivers unipolar energy between a lattice‐tip catheter and a cutaneous return patch, potentially generating a broader electric field. We hypothesized that this may attenuate voltage beyond...

A multicenter phase II trial of ramucirumab plus irinotecan for early recurrence of gastric cancer during or after adjuvant chemotherapy with docetaxel plus S-1 therapy: the RAMIEL trial (OGSG1901)

Abstract Background There is currently no established chemotherapy regimen for early recurrence of pathological stage III gastric cancer (GC) following adjuvant chemotherapy with docetaxel plus S-1 (DS) after D2 gastrectomy. We aimed to evaluate the efficacy and safety of ramucir...

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other embryonal tumors

WHO CNS5 mandates integrated histo-molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low- and lower-middle-income countries (LICs/LMICs), limiting implementation of molecularly in...

Treatment-dependent and independent prognostic value of inflammation-based nutritional indices in immune checkpoint inhibitor-based therapy for esophageal cancer

Abstract Background Phase III trials have established the efficacy of immune-based therapies for unresectable advanced or recurrent esophageal squamous cell carcinoma (ESCC). However, real-world evidence comparing regimens and clinically applicable prognostic biomarkers remains l...