Organogenesis (United States)

Silent Mutation Misclassification and Unrecorded Covalent Bonds in the Protein Data Bank

Sequence differences between deposited macromolecular models and their UniProt references are recorded in the mmCIF category _struct_ref_seq_dif, and intentional substitutions are expected to populate _entity_poly.pdbx_mutation, the field that structured queries read. When a subs...

Latent tuberculosis infection shapes gut microbiome and immune-metabolic interactions in people living with HIV

The silent presence of latent tuberculosis infection (LTBI) in people living with HIV (PLHIV) increases the annual risk of tuberculosis (TB) reactivation by 3%–16%. Although gut dysbiosis is well documented in HIV, microbiome alterations associated with LTBI in PLHIV remain poorl...