Örebro University

Doctoral Thesis Review – Anmeldelse av doktoravhandling

On 13 March 2026, Linnea Saltin defended her thesis entitled Ektopic: A Phenomenology of Domestic VR usage in Sweden. The central purpose of this work is to explore how Virtual Reality (VR) affects...

Prehospital Variables Do Not Reliably Identify Pelvic Fracture Morphologies Amenable to Pelvic Binder Application: A Retrospective Imaging Review

Background Pelvic binders are used in prehospital settings for early stabilization when pelvic fractures are suspected. Although a rapid and cost-effective tool, uncertainties persist regarding their use prior to radiological confirmation of pelvic fracture. Methods A review of a...

Risk factors of post-COVID-19 symptoms, a cross-sectional study in patients with asthma and chronic obstructive lung disease

Post-COVID-19 symptoms are common following COVID-19, but risk factors of persistent symptoms in patients with asthma and chronic obstructive lung disease (COPD) remain unclear. We aimed to assess the frequency and risk factors of post-COVID-19 symptoms in patients with asthma an...

High‐ versus low‐frequency exercise for depression in university students: a single‐blind randomized controlled trial

Background The core affect (CA) hypothesis posits that exercise serves either to increase positive affect or reduce negative affect. One rarely examined implication of the CA hypothesis is that multiple short exercise bouts distributed throughout the week, rather than one long tr...

Long-term Trends in Upper Gastrointestinal Bleeding and Ischemic Outcomes after Myocardial Infarction

Abstract Aims Invasive management and intensive antithrombotic regimens have decreased ischemic risk after myocardial infarction (MI) at the cost of more bleeding. Of particular concern is upper gastrointestinal bleeding (UGIB), which is both common and preventable, yet not well...

Major adverse cardiac events and mortality associated with ADHD and its treatment in adults with type 2 diabetes: a multi-national cohort study

Abstract Background Attention-deficit/hyperactivity disorder (ADHD) has been linked to elevated risk of type 2 diabetes (T2D). However, the impact of ADHD and ADHD medication use on prognosis and health outcomes in T2D remains unclear. This study investigates the associations of...

How I do it: microsurgical extraforaminal sequestrectomy through a midline intertransverse approach

Abstract Background Several surgical approaches exist for extraforaminal (far lateral) lumbar disc herniations, including paraspinal Wiltse-type, interlaminar, lateral intertransverse, and combined medial–lateral techniques. Method We present microsurgical extraforaminal sequestr...

High Risk of Metabolic Side Effects Among New Paediatric Antipsychotic Users in Sweden—A Register‐Based Study

PURPOSE: This study aims to assess the risk of metabolic side effects among paediatric new users of antipsychotics in Sweden, focusing on differences between substances and sexes. METHODS: Children aged 5-17 years, who were new users of antipsychotics between 2014 and 2021, were...

Lifetime substance use disorder and suicidal behaviour: a population-based familial co-aggregation register study

Abstract Substance use disorders (SUD) are associated with suicidal behaviour, but less is known regarding the extent to which familial factors influence these associations across different types of SUD. We performed a national register study including 4,209,615 individuals born...

Genome-wide analysis of social behaviour across social domains, reporters and developmental stages: a meta-regression approach

Abstract Social behaviour is a heritable trait linked to well-being and mental health, yet it varies across social context, including social domains, informants and development, which may shape its underlying genomic architecture. Here, we conducted a genome-wide meta-regression...

Is Screening of Adult Emergency Patients for Child Maltreatment Acceptable?

Data sharing not applicable to this article as no datasets were generated or analysed during the current study.

Bone morphogenetic protein 10 and one-year outcomes after open revascularisation in symptomatic peripheral arterial disease or carotid stenosis

Abstract Background Bone morphogenetic protein 10 (BMP10) has atrial-specific and vascular properties and may reflect both atrial and vascular pathophysiology. We investigated whether BMP10 levels were associated with new-onset atrial fibrillation (AF), major adverse cardiovascul...

The last duel? Out-of-court dispute settlement in EU content moderation

Court Dispute Settlement (ODS) bodies under Article 21 of the Digital Services Act (DSA) as a new remedial mechanism for users contesting content moderation decisions. While these bodies operate within the EU's broader approach to alternative dispute resolution (ADR), they create...

Assessing ethical competence and ethical climate: development and psychometric testing of the Clinical Ethics Support Measurement Instrument (CES-MI)

Abstract Background Clinical ethics support (CES) is increasingly recognised as essential in healthcare, yet its evaluation remains challenging due to the complexity of CES practices and the latent, psychosocial nature of relevant outcomes. The European Moral Case Deliberation Ou...

Metoprolol in Chronic Obstructive Pulmonary Disease without Cardiovascular Disease

BACKGROUND: Beta-blockers may improve outcomes in patients with chronic obstructive pulmonary disease (COPD) without cardiovascular disease, but randomized trials have been inconclusive. METHODS: This was a multicenter, open-label, pragmatic, phase 4 randomized trial. Patients 40...

Development and external validation of a machine-learning risk model for colorectal cancer triage in Sweden’s fast-track pathway

Abstract Background Fast-track colonoscopy pathways detect colorectal cancer (CRC) but strain endoscopy capacity. We developed and externally validated multivariable risk models combining faecal immunochemical test (FIT) with clinical data to triage Swedish fast-track referrals....

Difficult-to-treat systemic lupus erythematosus: from refractory disease to a multidimensional clinical trajectory

Difficult-to-treat (D2T) systemic lupus erythematosus (SLE) is increasingly recognised in clinical practice but is still conceptually underdeveloped. In contrast to rheumatoid arthritis and psoriatic arthritis, for which formal D2T frameworks have been proposed, SLE still lacks a...

Early life predictors of subjective cognitive function in older age: Emerging longitudinal associations over six decades

Abstract Objectives Self-rated memory impairment is common in older age and has been related to objective cognitive decline and dementia. Recently, there has been growing interest in early-life predictors of late-life cognition, but research has been limited due to the absence of...

Artificial intelligence in mathematics education: a two-dimensional conceptual framework and meta-review

Abstract Artificial Intelligence (AI) is transforming mathematics education just as it is reshaping many other domains of modern life, creating new opportunities that fundamentally change the way students and teachers work. AI has become an increasingly prominent topic in mathema...

Familial Co‐Aggregation of Neurodevelopmental Conditions and Childhood‐Onset Type 1 Diabetes

ABSTRACT Aim Childhood‐onset Type 1 diabetes (T1D) is associated with neurodevelopmental conditions (NDCs). We examined whether this association extends to relatives and assessed phenotypic, genetic, and environmental correlations between T1D and NDCs. Methods Using Swedish regis...