Okan University

Performance Enhancement of Solar Stills Using Wire‐Mesh Materials: A Systematic Review of Passive, Hybrid, and Active Approaches

ABSTRACT Solar still (SS) desalination is a solar‐based desalination technology that is environmentally friendly and has the potential to provide an abundant supply of saline water, but has been limited in practice due to low productivity and thermal efficiency. This systematic r...

Acromegaly as the Initial Presentation of Multiple Endocrine Neoplasia Type 1: A Case Report

BACKGROUND Multiple endocrine neoplasia syndrome type 1 (MEN-1) is a rare autosomal-dominant disorder, caused by MEN-1 gene mutations, leading to tumors in multiple endocrine organs, classically the parathyroid glands, the anterior pituitary, and the pancreatic islet cells. Altho...

Association of Gastric Microbiota with Gastric Cancer in Patients Infected with Helicobacter pylori

Background: The association between Helicobacter pylori and the resident gastric microbiota plays a critical role in gastric carcinogenesis; however, the specific microbial alterations accompanying the transition from chronic inflammation to malignancy remain to be fully elucidat...

Explainable Machine Learning for Prediction of Future High-Severity States Using Longitudinal APACHE-II Trajectories: Internal Validation and Cross-Cohort Portability Assessment

Background: Longitudinal severity assessment may provide more informative risk stratification than reliance on a single admission score in intensive care. This study developed and internally validated an explainable machine learning framework for predicting a subsequent APACHE-II...

Tissue Transglutaminase (TG2) as a Candidate Biomarker and Potential Therapeutic Target in Endometriosis: Functional Evidence from shRNA-Mediated Downregulation of TG2 in Endometrial Mesenchymal Stem Cells

Background/Objectives: Endometriosis involves the presence of endometrial tissue outside the uterus. Since the migration of endometrial cells is pivotal to lesion development, tissue transglutaminase (TG2)—known for its roles in cell adhesion, migration, and stemness—may play a s...

Do Free-Living Amoebae Serve as a Shelter for Helicobacter pylori in Istanbul’s Water Treatment Plants?

Understanding microbial survival mechanisms in aquatic environments is essential for public health. This study investigates the potential role of free-living amoebae (FLA) as environmental shelters for Helicobacter pylori in Istanbul’s potable and wastewater treatment plants. Sam...

Buckling of carbon nanotubes using molecular dynamics simulation: Investigating the effect of boron doping by considering the interaction energy

This study investigates the atomic-scale stability and buckling behavior of boron-doped carbon nanotubes (CNTs) using molecular dynamics simulations. After equilibration in the NVT ensemble, we applied compressive deformation to evaluate the mechanical response and structural evo...

Detection-Guided ROI-Constrained Diffusion for Weakly Supervised White Blood Cell Segmentation: A Retrospective Internal and External Dataset Evaluation

Background: Accurate white blood cell (WBC) segmentation is important for quantitative microscopic image analysis, but conventional supervised approaches depend on labor-intensive pixel-level annotations and may exhibit reduced robustness across datasets. This study proposes a de...

RELATIONSHIP BETWEEN CRANIOFACIAL SKELETAL MORPHOLOGY AND FREEWAY SPACE IN ADULTS: A CEPHALOMETRIC AND CLINICAL STUDY

Abstract Aim: Freeway space (FWS), the difference between rest vertical dimension and occlusal vertical dimension, is a clinically important component of vertical dimension assessment. Because mandibular rest position reflects a dynamic neuromuscular balance, an objective skeleta...

RELATIONSHIP BETWEEN CRANIOFACIAL SKELETAL MORPHOLOGY AND FREEWAY SPACE IN ADULTS: A CEPHALOMETRIC AND CLINICAL STUDY

Abstract Aim: Freeway space (FWS), the difference between rest vertical dimension and occlusal vertical dimension, is a clinically important component of vertical dimension assessment. Because mandibular rest position reflects a dynamic neuromuscular balance, an objective skeleta...

CBT-ICU transformer: a clinician-behaviour-aware multimodal deep learning framework for early detection of critical care adverse events in MIMIC-IV

Early identification of clinical deterioration in intensive care units (ICUs) remains a major challenge despite the availability of large-scale electronic health records. Most existing models focus primarily on physiological measurements such as vital signs and laboratory results...

Seminal Plasma Kisspeptin‐1 and Kisspeptin‐54 Levels Are Associated With Semen Parameters and Oxidative Stress in Male Infertility

ABSTRACT Objective Kisspeptin‐1 and Kisspeptin‐54 are key regulators of the hypothalamic–pituitary–gonadal axis and may play a role in male reproductive function. This study aimed to evaluate the association between seminal plasma kisspeptin levels and male infertility, and to ex...

Fluxus and Artists' Publications: The Case of Grapefruit

Fluxus artists sought to transform artistic production into a form that was more accessible, reproducible, and closely connected to everyday life by challenging art’s dependence on institutional spaces, market relations, and traditional aesthetic hierarchies. Within this framewor...

The Impact of AI-Assisted Adaptive Training Approach on Radiation Safety Competence in Healthcare Workers

Aim: The aim of this study is to evaluate the effect of an artificial intelligence (AI)- based adaptive training model on the radiation safety competence (knowledge, attitude, and protective behavior) of healthcare professionals.Method: The research was conducted in a quasi-exper...