Office Of Health Economics

Does EQ-5D measure the most relevant aspects of health across cultures? Findings from a multi-country qualitative and card-sorting study

The EQ-5D is a widely used measure of health-related quality of life (HRQoL) in health services and economic evaluations globally. However, its cross-cultural content validity remains underexplored. This study assesses the relevance and adequacy of EQ-5D across diverse cultural c...

Factors influencing FDA drug approval decisions beyond clinical trial evidence: a scoping review

Abstract Introduction The Food and Drug Administration’s (FDA) approval decisions are expected to rest primarily on clinical evidence, yet concerns persist about whether political pressure, commercial interests, or institutional dynamics also influence the approval process. Metho...