October University of Modern Sciences and Arts

Gamma Irradiation-Induced Synthesis of Dextrin/N-Vinylpyrrolidone Biohydrogel for High-Efficiency Adsorptive Removal of Nitrofurantoin and Methylene Blue from Aqueous Media

Biomedical pollutants, including pharmaceutical residues such as nitrofurantoin (NF) and medical dyes such as methylene blue (MB), are increasingly detected in surface water and wastewater, posing environmental and health concerns due to their durability and biological activity....

A novel repurposing opportunity for valsartan: angiotensin II type 1 receptor blockade dampens muscle-to-brain sensitization in fibromyalgia by targeting lncRNA H19/miR-29a-3p, inflammatory mediators, AKT/CREB signaling, neurotrophic factors, and amyloid–Tau pathology

Fibromyalgia (FM) is a debilitating nociplastic pain disorder increasingly recognized to involve skeletal muscle as an active contributor to peripheral nociception and central sensitization rather than a passive target of disease. Although angiotensin II promotes pain signaling t...

Ethnopharmacological insights into type 2 diabetes management by traditional Moroccan herbal teas: HPLC-MS characterization of phenolic compounds and their related antioxidant and enzyme inhibitory activities

Abstract Background Traditional Moroccan herbal teas are widely consumed and have been traditionally used for managing chronic metabolic disorders, particularly type 2 diabetes mellitus (T2DM). Although these preparations have a long history of ethnomedicinal use, their phenolic...

Development and Optimisation Using D-Optimal Design of Dual-Functionalized Hyaluronic Acid–Chitosan-Coated Mesoporous Silica Nanoparticles for Repurposed Propranolol Delivery in Breast Cancer: A Proof-of-Concept Study

Drug repurposing combined with nanocarrier systems can accelerate cancer therapy development while reducing the time and cost of conventional drug discovery. We developed and optimised hyaluronic acid (HA)–chitosan (CH)-coated mesoporous silica nanoparticles (HA-CH-Prop-MSNPs) fo...

Shariah index inclusion and stock returns in Egypt: an event study of the EGX33 Shariah Index across sectors

Purpose This study examines the impact of inclusion in the EGX33 Shariah Index on the stock returns of listed Egyptian companies, with a focus on sector-specific effects. It explores whether such inclusion generates abnormal returns, contributing to ethical and Shariah-compliant...

Evaluation the role of quinoa seeds in attenuation the brain cellular senescence and aging induced by D-galactose and γ-radiation in rats: insights into autophagy, telomerase activity, amyloid-β and tau proteins

The gradual loss of cognitive function, manifested by impaired learning and spatial memory, is a hallmark of brain senescence during aging. However, effective natural interventions targeting multiple mechanisms involved in aging-related neurodegeneration remain limited. This stud...

Integrating Sustainability, Biodiversity, and Human Health to Improve Indoor University Spaces: A Comparative Case Study Using Real-Time Environmental Monitoring and AI-Driven Analysis

Climate Change (CC) has increasingly disrupted the global environment, with significant consequences for biodiversity, cities, and human health and well-being over the past decades. Mitigating anthropogenic emissions and promoting healthier, more sustainable built environments ar...

A Systematic Multi-Dataset, Multi-Seed Evaluation of Preprocessing Strategies for Retinal Optic Disc and Cup Segmentation

Background/Objectives: Accurate delineation of the optic disc and optic cup in retinal fundus photographs is a prerequisite for automated glaucoma screening. While encoder–decoder segmentation models have advanced considerably, the contribution of upstream preprocessing to segmen...

A novel technique for automatic hybrid modulation classification in UWA communications using 3D constellation diagrams

Abstract Underwater acoustic (UWA) communication systems operate in severe channel impairments, including strong multipath propagation, long delay spreads, frequency selectivity, Doppler effects, and high ambient noise. These challenges significantly complicate automatic modulati...