Nuremberg Hospital

Comorbidity management in inflammatory rheumatic diseases: a dual-perspective survey of patients and rheumatologists

Abstract Background Comorbidities are major contributors to morbidity and mortality in patients with inflammatory rheumatic diseases (IRDs). We assessed real-world implementation of European Alliance of Associations for Rheumatology (EULAR) points to consider for comorbidity mana...

Exploring Pathophysiological Processes Shared Between Type 2 Diabetes Mellitus and Osteoarthritis

Type 2 diabetes mellitus (T2DM) and osteoarthritis (OA) are highly prevalent chronic disorders with increasing global burdens that frequently coexist and share common risk factors, including obesity, aging and chronic low-grade inflammation. This narrative review aims to summariz...

Development and Nationwide Multicentre Evaluation of Guideline-Grounded Large Language Model Chatbots to Support Patient Self-Management and Education in Rheumatology

Patients with rheumatic diseases have persistent information needs that are not fully addressed in routine care. We developed and evaluated guideline-grounded, large language model (LLM) chatbots to support patient self-management and education in rheumatology.Ten disease-specifi...

Clinical outcomes following a hospital-wide transition from enoxaparin to tinzaparin for venous thromboembolism prophylaxis in neurosurgical patients

Abstract Objective Venous thromboembolism (VTE) prophylaxis is a key component of neurosurgical care, with low-molecular-weight heparins (LMWHs) representing the standard pharmacological approach. While enoxaparin is well established, the evidence regarding the efficacy and safet...

Ventromedial prefrontal cortex attenuates the link between physiological heart rate reactions to unfairness and value computations in normative decision making

Abstract Emotional reactions to norm violations influence how people trade-off selfish interests against social norms, but it remains unknown which brain regions contribute to integrating physiological (e.g., heart rate) responses to norm violations into the decision process. Her...

“Made with AI” but why? How consumers interpret beneficiary-framed AI disclosures in advertising

Abstract As generative AI becomes more prevalent in advertising, firms increasingly face requirements to disclose AI involvement. Although prior research shows that such disclosures may generate negative consumer responses, it remains unclear whether explanatory disclosures can m...

A Surgical Algorithm for Upper Cervical Trauma Based on the AO Spine Upper Cervical Injury Classification System

Study Design. Global cross-sectional survey Objective. To establish a surgical algorithm for upper cervical spine injuries using the AO Spine Upper Cervical Injury Classification (UCIC) system, defining operative thresholds using a novel proposed Upper Cervical AO-Spine Injury Sc...