Nuovo Ospedale San Giovanni di Dio

Real-world adjunctive use of an alpha-lactalbumin/sodium butyrate Food for Special Medical Purposes in drug-resistant epilepsy: the multicentre retrospective ARMILLA study

The purpose of this study was to describe real-world adjunctive use, tolerability, and hypothesis-generating seizure and multidomain outcomes of LALBAAY, an alpha-lactalbumin/sodium butyrate Food for Special Medical Purposes (FSMP), in patients with drug-resistant epilepsy (DRE)....

LLM-Based Chatbots and the Suicidal Crisis: A Bi-Logical Account of Relational Hallucination

A series of documented deaths by suicide following prolonged interactions with chatbots based on large language models (LLMs) has exposed the clinical risks of delegating emotional support to conversational artificial intelligence. This paper proposes a psychodynamic account of t...

Predicting the risk of dehydration and readmission among rectal cancer patients with ileostomy: a multicenter observational study

Abstract Dehydration is a frequent complication among rectal cancer patients after ileostomy, often resulting in hospital readmission. The Dehydration Readmission after Ileostomy Prediction (DRIP) score was used to identify patients at risk of dehydration-related readmission. The...

A Novel Constitutional TUBB Variant Associated With Familial Malformations of Cortical Development

ABSTRACT Most pathogenic tubulin variants arise de novo in sporadic patients, causing severe brain malformations and significant neurodevelopmental impairment. The resulting reproductive disadvantage typically prevents these mutations from being transmitted to offspring. While a...